• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

基于卷积变分自动编码器的心电图数据无监督特征学习。

Unsupervised feature learning for electrocardiogram data using the convolutional variational autoencoder.

机构信息

Department of Biomedical Systems Informatics, Yonsei University College of Medicine, Yongin, Gyeonggi-do, Republic of Korea.

BUD.on Inc, Jeonju, Republic of Korea.

出版信息

PLoS One. 2021 Dec 1;16(12):e0260612. doi: 10.1371/journal.pone.0260612. eCollection 2021.

DOI:10.1371/journal.pone.0260612
PMID:34852002
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8635334/
Abstract

Most existing electrocardiogram (ECG) feature extraction methods rely on rule-based approaches. It is difficult to manually define all ECG features. We propose an unsupervised feature learning method using a convolutional variational autoencoder (CVAE) that can extract ECG features with unlabeled data. We used 596,000 ECG samples from 1,278 patients archived in biosignal databases from intensive care units to train the CVAE. Three external datasets were used for feature validation using two approaches. First, we explored the features without an additional training process. Clustering, latent space exploration, and anomaly detection were conducted. We confirmed that CVAE features reflected the various types of ECG rhythms. Second, we applied CVAE features to new tasks as input data and CVAE weights to weight initialization for different models for transfer learning for the classification of 12 types of arrhythmias. The f1-score for arrhythmia classification with extreme gradient boosting was 0.86 using CVAE features only. The f1-score of the model in which weights were initialized with the CVAE encoder was 5% better than that obtained with random initialization. Unsupervised feature learning with CVAE can extract the characteristics of various types of ECGs and can be an alternative to the feature extraction method for ECGs.

摘要

大多数现有的心电图(ECG)特征提取方法都依赖于基于规则的方法。手动定义所有 ECG 特征是很困难的。我们提出了一种使用卷积变分自动编码器(CVAE)的无监督特征学习方法,该方法可以使用未标记的数据提取 ECG 特征。我们使用了来自重症监护病房生物信号数据库中的 1278 名患者的 596000 个 ECG 样本来训练 CVAE。我们使用了三个外部数据集,通过两种方法进行特征验证。首先,我们在没有额外训练过程的情况下探索了特征。进行了聚类、潜在空间探索和异常检测。我们确认 CVAE 特征反映了各种类型的 ECG 节律。其次,我们将 CVAE 特征作为输入数据应用于新任务,并将 CVAE 权重应用于不同模型的权重初始化,以进行心律失常分类的迁移学习。仅使用 CVAE 特征进行极端梯度提升的心律失常分类的 f1 分数为 0.86。使用 CVAE 编码器初始化权重的模型的 f1 分数比随机初始化的分数高出 5%。使用 CVAE 进行无监督特征学习可以提取各种类型的 ECG 的特征,并且可以替代 ECG 的特征提取方法。

相似文献

1
Unsupervised feature learning for electrocardiogram data using the convolutional variational autoencoder.基于卷积变分自动编码器的心电图数据无监督特征学习。
PLoS One. 2021 Dec 1;16(12):e0260612. doi: 10.1371/journal.pone.0260612. eCollection 2021.
2
Effectiveness of Transfer Learning for Deep Learning-Based Electrocardiogram Analysis.基于深度学习的心电图分析中迁移学习的有效性
Healthc Inform Res. 2021 Jan;27(1):19-28. doi: 10.4258/hir.2021.27.1.19. Epub 2021 Jan 31.
3
CVAE-DF: A hybrid deep learning framework for fertilization status detection of pre-incubation duck eggs based on VIS/NIR spectroscopy.基于可见/近红外光谱的鸡胚蛋孵化状态检测的 CVAE-DF:一种混合深度学习框架。
Spectrochim Acta A Mol Biomol Spectrosc. 2024 Nov 5;320:124569. doi: 10.1016/j.saa.2024.124569. Epub 2024 May 31.
4
Unsupervised few shot learning architecture for diagnosis of periodontal disease in dental panoramic radiographs.基于无监督少样本学习的牙全景片牙周病诊断架构。
Sci Rep. 2024 Oct 5;14(1):23237. doi: 10.1038/s41598-024-73665-5.
5
A denoising method of ECG signal based on variational autoencoder and masked convolution.一种基于变分自编码器和掩码卷积的心电图信号去噪方法。
J Electrocardiol. 2023 Sep-Oct;80:81-90. doi: 10.1016/j.jelectrocard.2023.05.004. Epub 2023 May 18.
6
Deep clustering of protein folding simulations.蛋白质折叠模拟的深度聚类。
BMC Bioinformatics. 2018 Dec 21;19(Suppl 18):484. doi: 10.1186/s12859-018-2507-5.
7
Arrhythmia Classification Based on Multi-Domain Feature Extraction for an ECG Recognition System.基于多域特征提取的心律失常分类用于心电图识别系统
Sensors (Basel). 2016 Oct 20;16(10):1744. doi: 10.3390/s16101744.
8
Convolutional Autoencoding and Gaussian Mixture Clustering for Unsupervised Beat-to-Beat Heart Rate Estimation of Electrocardiograms from Wearable Sensors.卷积自动编码和高斯混合聚类在可穿戴传感器心电图无监督逐拍心率估计中的应用。
Sensors (Basel). 2021 Oct 28;21(21):7163. doi: 10.3390/s21217163.
9
A novel automatic detection system for ECG arrhythmias using maximum margin clustering with immune evolutionary algorithm.一种基于最大间隔聚类和免疫进化算法的新型心电图心律失常自动检测系统。
Comput Math Methods Med. 2013;2013:453402. doi: 10.1155/2013/453402. Epub 2013 Apr 18.
10
12-Lead ECG arrhythmia classification using cascaded convolutional neural network and expert feature.基于级联卷积神经网络和专家特征的 12 导联心电图心律失常分类
J Electrocardiol. 2021 Jul-Aug;67:56-62. doi: 10.1016/j.jelectrocard.2021.04.016. Epub 2021 May 26.

引用本文的文献

1
Unsupervised deep learning of electrocardiograms enables scalable human disease profiling.心电图的无监督深度学习可实现可扩展的人类疾病特征分析。
NPJ Digit Med. 2025 Jan 12;8(1):23. doi: 10.1038/s41746-024-01418-9.
2
Unsupervised few shot learning architecture for diagnosis of periodontal disease in dental panoramic radiographs.基于无监督少样本学习的牙全景片牙周病诊断架构。
Sci Rep. 2024 Oct 5;14(1):23237. doi: 10.1038/s41598-024-73665-5.
3
Exploring unsupervised feature extraction of IMU-based gait data in stroke rehabilitation using a variational autoencoder.

本文引用的文献

1
Automatic multilabel electrocardiogram diagnosis of heart rhythm or conduction abnormalities with deep learning: a cohort study.深度学习自动多标签心电图诊断心律失常或传导异常:一项队列研究。
Lancet Digit Health. 2020 Jul;2(7):e348-e357. doi: 10.1016/S2589-7500(20)30107-2. Epub 2020 Jun 4.
2
Clustering with t-SNE, provably.使用t-SNE进行聚类,可证明。
SIAM J Math Data Sci. 2019;1(2):313-332. doi: 10.1137/18m1216134. Epub 2019 May 28.
3
Artificial Intelligence-Enabled ECG: a Modern Lens on an Old Technology.人工智能心电图:旧技术的新视角。
使用变分自编码器探索基于 IMU 的中风康复步态数据的无监督特征提取。
PLoS One. 2024 Oct 4;19(10):e0304558. doi: 10.1371/journal.pone.0304558. eCollection 2024.
4
Diagnosis of atrial fibrillation based on AI-detected anomalies of ECG segments.基于人工智能检测到的心电图段异常诊断心房颤动。
Heliyon. 2023 Dec 12;10(1):e23597. doi: 10.1016/j.heliyon.2023.e23597. eCollection 2024 Jan 15.
5
Improving explainability of deep neural network-based electrocardiogram interpretation using variational auto-encoders.使用变分自编码器提高基于深度神经网络的心电图解释的可解释性。
Eur Heart J Digit Health. 2022 Jul 25;3(3):390-404. doi: 10.1093/ehjdh/ztac038. eCollection 2022 Sep.
Curr Cardiol Rep. 2020 Jun 19;22(8):57. doi: 10.1007/s11886-020-01317-x.
4
A 12-lead electrocardiogram database for arrhythmia research covering more than 10,000 patients.一个包含超过 10000 名患者的心律失常研究用 12 导联心电图数据库。
Sci Data. 2020 Feb 12;7(1):48. doi: 10.1038/s41597-020-0386-x.
5
Effect of Watch-Type Haptic Metronome on the Quality of Cardiopulmonary Resuscitation: A Simulation Study.手表式触觉节拍器对心肺复苏质量的影响:一项模拟研究。
Healthc Inform Res. 2019 Oct;25(4):274-282. doi: 10.4258/hir.2019.25.4.274. Epub 2019 Oct 31.
6
An artificial intelligence-enabled ECG algorithm for the identification of patients with atrial fibrillation during sinus rhythm: a retrospective analysis of outcome prediction.一种基于人工智能的心电图算法,用于在窦性心律期间识别房颤患者:对结局预测的回顾性分析。
Lancet. 2019 Sep 7;394(10201):861-867. doi: 10.1016/S0140-6736(19)31721-0. Epub 2019 Aug 1.
7
Screening for cardiac contractile dysfunction using an artificial intelligence-enabled electrocardiogram.使用人工智能心电图筛查心脏收缩功能障碍。
Nat Med. 2019 Jan;25(1):70-74. doi: 10.1038/s41591-018-0240-2. Epub 2019 Jan 7.
8
Constructing an Open-Access Bio-Signal Repository from Intensive Care Units.构建重症监护病房的开放获取生物信号库。
Stud Health Technol Inform. 2017;245:1271.
9
ST elevation: differentiation between ST elevation myocardial infarction and nonischemic ST elevation.ST段抬高:ST段抬高型心肌梗死与非缺血性ST段抬高的鉴别
J Electrocardiol. 2011 Sep-Oct;44(5):494.e1-494.e12. doi: 10.1016/j.jelectrocard.2011.06.002.
10
A simple method to detect atrial fibrillation using RR intervals.一种使用 RR 间期检测心房颤动的简单方法。
Am J Cardiol. 2011 May 15;107(10):1494-7. doi: 10.1016/j.amjcard.2011.01.028. Epub 2011 Mar 17.