新型大环内酯类抗生素罗红霉素（RU 28965）对流感嗜血杆菌临床分离株的体外活性
In vitro activity of the new macrolide antibiotic roxithromycin (RU 28965) against clinical isolates of Haemophilus influenzae.
作者信息
Jorgensen J H, Redding J S, Howell A W
出版信息
Antimicrob Agents Chemother. 1986 May;29(5):921-2. doi: 10.1128/AAC.29.5.921.
Abstract
The in vitro activity of the new macrolide antibiotic roxithromycin (RU 28965) was compared with the activities of five other orally absorbable antimicrobial agents against 100 clinical isolates of Haemophilus influenzae. Roxithromycin MICs were generally twofold to fourfold higher than those of erythromycin; the MIC for 90% of the strains for roxithromycin was 8 micrograms/ml.
摘要
将新型大环内酯类抗生素罗红霉素（RU 28965）的体外活性与其他五种口服可吸收抗菌剂对100株流感嗜血杆菌临床分离株的活性进行了比较。罗红霉素的最低抑菌浓度（MIC）通常比红霉素高2至4倍；罗红霉素对90%菌株的MIC为8微克/毫升。
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