Serbezeanu Diana, Bargan Alexandra, Homocianu Mihaela, Aflori Magdalena, Rîmbu Cristina Mihaela, Enache Alexandru Alin, Vlad-Bubulac Tăchiță
"Petru Poni" Institute of Macromolecular Chemistry, 41A, Grigore Ghica Voda Alley, 700487 Iasi, Romania.
Department of Public Health, Faculty of Veterinary Medicine "Ion Ionescu de la Brad", University of Agricultural Sciences and Veterinary Medicine, 8, Mihail Sadoveanu Alley, 707027 Iasi, Romania.
Nanomaterials (Basel). 2021 Dec 8;11(12):3336. doi: 10.3390/nano11123336.
In this paper, hydroalcoholic solutions of , , and were used in combination with poly (vinyl alcohol) with the aim of developing novel poly (vinyl alcohol)-based nanofiber mats loaded with phytotherapeutic agents via the electrospinning technique. The chemical structure and morphology of the polymeric nanofibers were investigated using Fourier Transform Infrared Spectroscopy (FTIR) and Scanning Electron Microscopy (SEM). The addition of , , and extracts to the pure polyvinyl alcohol fibers led to changes in the morphology of the fibers and a reduction in the fibers' diameter, from 0.1798 µm in the case of pure polyvinyl alcohol to 0.1672, 0.1425, and 0.1369 µm in the case of polyvinyl alcohol loaded with , , and , respectively. The adapted Folin-Ciocalteu (FC) method, which was used to determine the total phenolic contents, revealed that the samples of PVA- and PVA- had the highest phenol contents, at 13.25 μgGAE/mL and 12.66 μgGAE/mL, respectively. Dynamic water vapor measurements were used in order to investigate the moisture sorption and desorption behavior of the developed electrospun materials. The antimicrobial behavior of these products was also evaluated. Disk diffusion assay studies with , , and Methicillin-resistant were conducted on the developed nanofibers in order to quantify their phytotherapeutic potential.
在本文中，[此处原文未给出具体物质名称]、[此处原文未给出具体物质名称]和[此处原文未给出具体物质名称]的水醇溶液与聚乙烯醇结合使用，旨在通过静电纺丝技术开发负载植物治疗剂的新型聚乙烯醇基纳米纤维垫。使用傅里叶变换红外光谱（FTIR）和扫描电子显微镜（SEM）研究了聚合物纳米纤维的化学结构和形态。向纯聚乙烯醇纤维中添加[此处原文未给出具体物质名称]、[此处原文未给出具体物质名称]和[此处原文未给出具体物质名称]提取物导致纤维形态发生变化，纤维直径减小，从纯聚乙烯醇的0.1798 µm分别降至负载[此处原文未给出具体物质名称]、[此处原文未给出具体物质名称]和[此处原文未给出具体物质名称]的聚乙烯醇的0.1672 µm、0.1425 µm和0.1369 µm。用于测定总酚含量的改良福林 - 西奥尔特（FC）法表明，PVA - [此处原文未给出具体物质名称]和PVA - [此处原文未给出具体物质名称]样品的酚含量最高，分别为13.25 μgGAE/mL和12.66 μgGAE/mL。使用动态水蒸气测量来研究开发的电纺材料的吸湿和解吸行为。还评估了这些产品的抗菌性能。对开发的纳米纤维进行了针对[此处原文未给出具体物质名称]、[此处原文未给出具体物质名称]和耐甲氧西林[此处原文未给出具体物质名称]的纸片扩散试验研究，以量化其植物治疗潜力。
