Horii A, Kobayashi T, Tomita N, Yamamoto T, Fukushige S, Murotsu T, Ogawa M, Mori T, Matsubara K
Institute for Molecular and Cellular Biology, Osaka University, Suita, Japan.
Biochem Biophys Res Commun. 1987 Dec 16;149(2):635-41. doi: 10.1016/0006-291x(87)90415-3.
The human pancreatic secretory trypsin inhibitor (PSTI) gene was isolated from a human gene library. Restriction endonuclease mapping and DNA sequencing analysis revealed that this gene is approximately 7.5 kb long and is separated into four exons by three introns. The gene has multiple transcription start points and examination with a single-laser cell-sorter showed that it is located on chromosome 5.
人胰腺分泌型胰蛋白酶抑制剂(PSTI)基因是从人基因文库中分离出来的。限制性内切酶图谱分析和DNA测序分析表明,该基因长度约为7.5 kb,被3个内含子分隔为4个外显子。该基因有多个转录起始点,用单激光细胞分选仪检测表明它位于5号染色体上。