Salter D M, Krajewski A S, Dewar A E
J Clin Pathol. 1986 Jan;39(1):8-15. doi: 10.1136/jcp.39.1.8.
Five cases of malignant histiocytosis of the intestine and one case of true histiocytic lymphoma were studied using immunohistological techniques. In paraffin sections tumour cells in all cases were shown to contain alpha-1-antitrypsin and to express the leucocyte common antigen. Four of the five cases of malignant histiocytosis of the intestine and the case of histiocytic lymphoma expressed the epithelial membrane antigen. Cryostat sections in four cases of malignant histiocytosis of the intestine showed that most tumour cells reacted with anti-T cell monoclonal antibodies. Only a minority expressed a typical monocyte macrophage phenotype.
运用免疫组织学技术对5例肠道恶性组织细胞增多症和1例真性组织细胞淋巴瘤进行了研究。在石蜡切片中，所有病例的肿瘤细胞均显示含有α-1-抗胰蛋白酶并表达白细胞共同抗原。5例肠道恶性组织细胞增多症中的4例以及组织细胞淋巴瘤病例表达上皮膜抗原。4例肠道恶性组织细胞增多症的冰冻切片显示，大多数肿瘤细胞与抗T细胞单克隆抗体发生反应。只有少数细胞表达典型的单核细胞巨噬细胞表型。
