Ananda Thripthi, Modi Ankita, Chakraborty Ishita, Managuli Vishwanath, Mukhopadhyay Chiranjay, Mazumder Nirmal
Department of Microbiology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India.
Department of Applied Mechanics, Indian Institute of Technology Madras, Chennai 600036, Tamil Nadu, India.
Bioengineering (Basel). 2022 Jan 28;9(2):51. doi: 10.3390/bioengineering9020051.
Nosocomial infections, termed hospital-acquired infections (HAIs), are acquired from a healthcare or hospital setting. HAI is mainly caused by bacteria, such as , , , spp., Methicillin-resistant (MRSA), and many more. Due to growing antibacterial resistance, nanotechnology has paved the way for more potent and sensitive methods of detecting and treating bacterial infections. Nanoparticles have been used with molecular beacons for identifying bactericidal activities, targeting drug delivery, and anti-fouling coatings, etc. This review addresses the looming threat of nosocomial infections, with a focus on the Indian scenario, and major initiatives taken by medical bodies and hospitals in spreading awareness and training. Further, this review focuses on the potential role nanotechnology can play in combating the spread of these infections.
医院感染，又称医院获得性感染（HAIs），是在医疗保健机构或医院环境中获得的。医院获得性感染主要由细菌引起，如 、 、 、 属细菌、耐甲氧西林金黄色葡萄球菌（MRSA）等等。由于抗菌耐药性不断增加，纳米技术为检测和治疗细菌感染提供了更有效、更灵敏的方法。纳米颗粒已与分子信标一起用于识别杀菌活性、靶向给药和防污涂层等。本综述探讨了医院感染迫在眉睫的威胁，重点关注印度的情况，以及医疗机构和医院在提高认识和培训方面采取的主要举措。此外，本综述着重探讨了纳米技术在对抗这些感染传播方面可能发挥的潜在作用。
