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肠道微生物群在儿童身体生长中的中介作用。

The Mediating Role of the Gut Microbiota in the Physical Growth of Children.

作者信息

Durda-Masny Magdalena, Ciomborowska-Basheer Joanna, Makałowska Izabela, Szwed Anita

机构信息

Institute of Human Biology and Evolution, Faculty of Biology, Adam Mickiewicz University, 61-614 Poznan, Poland.

出版信息

Life (Basel). 2022 Jan 20;12(2):152. doi: 10.3390/life12020152.

Abstract

Gut microbiota succession overlaps with intensive growth in infancy and early childhood. The multitude of functions performed by intestinal microbes, including participation in metabolic, hormonal, and immune pathways, makes the gut bacterial community an important player in cross-talk between intestinal processes and growth. Long-term disturbances in the colonization pattern may affect the growth trajectory, resulting in stunting or wasting. In this review, we summarize the evidence on the mediating role of gut microbiota in the mechanisms controlling the growth of children.

摘要

肠道微生物群的演替与婴儿期和幼儿期的快速生长相重叠。肠道微生物执行的众多功能,包括参与代谢、激素和免疫途径,使肠道细菌群落成为肠道过程与生长之间相互作用的重要参与者。定植模式的长期紊乱可能会影响生长轨迹,导致发育迟缓或消瘦。在这篇综述中,我们总结了关于肠道微生物群在控制儿童生长机制中的中介作用的证据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72a2/8880549/edfdbe3b651c/life-12-00152-g001.jpg

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