School of Life Science and Engineering, Foshan University, Foshan 528225, China.
College of Animal Science and Technology, Zhongkai University of Agriculture and Engineering, Guangzhou 510230, China.
Viruses. 2023 Aug 8;15(8):1705. doi: 10.3390/v15081705.
currently encompasses seven genera and 53 species. Multiple hantaviruses such as Hantaan virus, Seoul virus, Dobrava-Belgrade virus, Puumala virus, Andes virus, and Sin Nombre virus are highly pathogenic to humans. They cause hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome or hantavirus pulmonary syndrome (HCPS/HPS) in many countries. Some hantaviruses infect wild or domestic animals without causing severe symptoms. Rodents, shrews, and bats are reservoirs of various mammalian hantaviruses. Recent years have witnessed significant advancements in the study of hantaviruses including genomics, taxonomy, evolution, replication, transmission, pathogenicity, control, and patient treatment. Additionally, new hantaviruses infecting bats, rodents, shrews, amphibians, and fish have been identified. This review compiles these advancements to aid researchers and the public in better recognizing this zoonotic virus family with global public health significance.
目前包含七个属和 53 个种。多种汉坦病毒，如汉坦病毒、汉城病毒、多布拉伐-贝尔格莱德病毒、普马拉病毒、安第斯病毒和辛诺柏病毒，对人类具有高度致病性。它们在许多国家引起肾综合征出血热（HFRS）和汉坦病毒心肺综合征或汉坦病毒肺综合征（HCPS/HPS）。一些汉坦病毒感染野生或家养动物而不引起严重症状。啮齿动物、鼩鼱和蝙蝠是各种哺乳动物汉坦病毒的宿主。近年来，汉坦病毒的研究取得了重大进展，包括基因组学、分类学、进化、复制、传播、致病性、控制和患者治疗。此外，还发现了感染蝙蝠、啮齿动物、鼩鼱、两栖动物和鱼类的新汉坦病毒。本综述汇集了这些进展，以帮助研究人员和公众更好地认识到具有全球公共卫生意义的这种人畜共患病毒家族。
