草药提取物与三联抗生素糊剂作为根管内药物的比较评价：一项微生物学研究

A Comparative Evaluation of Herbal Extracts and Triple Antibiotic Paste as Intracanal Medicament against A Microbiological Study.

作者信息

Golla Saritha, Gambhir Natasha, Gupta Nidhi, Singh Rashi, Singh Divya

机构信息

Department of Pediatric and Preventive Dentistry, Santosh Dental College & Hospital, Santosh (Deemed to be University), Ghaziabad, Uttar Pradesh, India.

出版信息

Int J Clin Pediatr Dent. 2024 Mar;17(3):285-290. doi: 10.5005/jp-journals-10005-2791.

DOI:10.5005/jp-journals-10005-2791

PMID:39144517

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11320791/

Abstract

PURPOSE

The purpose of the study is to compare and evaluate the efficacy of herbal extracts over modified triple antibiotic paste (MTAP) as intracanal medicaments against (). Ginger, turmeric, and nutmeg extract were checked for antibacterial activity by agar disk diffusion method at 100, 50, 25, and 12.5% concentration. Combination groups were prepared, and the combination group showing the best zone of inhibition was further evaluated.

MATERIALS AND METHODS

A total of 103 samples were taken and divided into five groups: group I-MTAP, group II-ginger, group III-turmeric, group IV-nutmeg, and group V-saline. Based on different concentrations, the groups were again subdivided into subgroups at 100, 50, 25, and 12.5%. Combination groups of ginger + nutmeg, ginger + turmeric, and turmeric + nutmeg were made and evaluated. The combination group showing the best zone of inhibition was again divided into 100, 50, 25, and 12.5% and further evaluated.

RESULTS

Modified triple antibiotic was effective in the elimination of Herbal extracts showed a reduction in the number of Nutmeg showed a reduction in followed by ginger, followed by turmeric.

CONCLUSION

This study shows that the combination of ginger + nutmeg at 12.5% concentration (35 mm) showed the highest zone of inhibition among all the herbal combinations, which is almost equal to that of MTAP.

HOW TO CITE THIS ARTICLE

Golla S, Gambhir N, Gupta N, A Comparative Evaluation of Herbal Extracts and Triple Antibiotic Paste as Intracanal Medicament against A Microbiological Study. Int J Clin Pediatr Dent 2024;17(3):285-290.

摘要

目的

本研究旨在比较和评估草药提取物与改良三联抗生素糊剂（MTAP）作为根管内药物对抗（）的疗效。采用琼脂纸片扩散法，在浓度为100%、50%、25%和12.5%时，检测生姜、姜黄和肉豆蔻提取物的抗菌活性。制备联合组，并对显示最佳抑菌圈的联合组进行进一步评估。

材料与方法

共采集103个样本，分为五组：第一组为MTAP组，第二组为生姜组，第三组为姜黄组，第四组为肉豆蔻组，第五组为生理盐水组。根据不同浓度，各组又进一步细分为浓度为100%、50%、25%和12.5%的亚组。制备并评估生姜+肉豆蔻、生姜+姜黄和姜黄+肉豆蔻的联合组。将显示最佳抑菌圈的联合组再次分为100%、50%、25%和12.5%的亚组，并进一步评估。