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摄入益生菌和含益生元的功能性食品所影响的肠道微生物群可维持健康并缓解某些疾病,如肠道炎症和结肠癌。

The Gut Microbiota Influenced by the Intake of Probiotics and Functional Foods with Prebiotics Can Sustain Wellness and Alleviate Certain Ailments like Gut-Inflammation and Colon-Cancer.

作者信息

Dahiya Divakar, Nigam Poonam Singh

机构信息

Wexham Park Hospital, Wexham Street, Slough SL2 4HL, Berkshire, UK.

Biomedical Sciences Research Institute, Ulster University, Coleraine BT52 1SA, Northern Ireland, UK.

出版信息

Microorganisms. 2022 Mar 20;10(3):665. doi: 10.3390/microorganisms10030665.

Abstract

The gut microbiota is composed of several microbial strains, with diverse and variable combinations in healthy and sick persons, changing at different stages of life. A healthy balance between host and gut microorganisms must be maintained in order to perform the normal physiological, metabolic, and immune functions and prevent disease development. Disturbances in the balance of the gut microbiota by diverse reasons initiate several health issues and promote the progression of certain diseases. This review is based on published research and reports that describe the role of probiotic microorganisms in the sustainability of health and the alleviation of certain diseases. Information is presented on the GRAS strains that are used as probiotics in the food industry for the production of fermented milk, yogurt, fermented food, functional foods, and probiotic drinks. To maintain a healthy microbiota, probiotic supplements in the form of freeze-dried live cells of probiotic strains are also available in different forms to consumers. The health benefits of lactic acid bacteria and other microorganisms and their role in the control of certain diseases such as gut inflammation, diabetes, and bowel cancer and in the safeguarding of the gut epithelial permeability from the invasion of pathogens are discussed.

摘要

肠道微生物群由多种微生物菌株组成,在健康人和病人中具有多样且可变的组合,并在生命的不同阶段发生变化。为了执行正常的生理、代谢和免疫功能并预防疾病发展,必须维持宿主与肠道微生物之间的健康平衡。多种原因导致的肠道微生物群平衡失调会引发多种健康问题,并促进某些疾病的进展。本综述基于已发表的研究和报告,这些研究和报告描述了益生菌微生物在维持健康和缓解某些疾病方面的作用。文中介绍了在食品工业中用作益生菌以生产发酵乳、酸奶、发酵食品、功能性食品和益生菌饮料的公认安全菌株。为了维持健康的微生物群,以益生菌菌株冻干活细胞形式存在的益生菌补充剂也以不同形式提供给消费者。文中讨论了乳酸菌和其他微生物的健康益处及其在控制某些疾病(如肠道炎症、糖尿病和肠癌)以及保护肠道上皮通透性免受病原体入侵方面的作用。

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