Marino Patricia, Touzani Rajae, Pakradouni Jihane, Ben Soussan Patrick, Gravis Gwenaelle
Institut Paoli-Calmettes, SESSTIM, INSERM, IRD, Aix Marseille University, 13009 Marseille, France.
Department of Clinical Research and Innovation, Institut Paoli-Calmettes, 13009 Marseille, France.
Cancers (Basel). 2022 Mar 31;14(7):1794. doi: 10.3390/cancers14071794.
Cancer patients commonly experience psychological distress that may increase with the current COVID-19 pandemic. This prospective study aimed to measure post-traumatic stress disorder (PTSD) and anxiety in cancer patients following France’s first COVID-19-related lockdown, together with associated factors. Cancer patients receiving outpatient treatment or post-treatment follow-up completed a questionnaire which measured, among other things, PTSD (IES-R), anxiety (State-Trait Anxiety Inventory), and fear of cancer recurrence (FCR). Of the 1097 patients included in the study, 14.7% and 30.5% suffered from PTSD and anxiety, respectively. Patients afraid to come to hospital due to the risk of COVID-19 transmission (OR = 3.49, p < 0.001), those with a negative lockdown experience (OR = 0.98, p < 0.001), women (OR = 1.97; p = 0.009), and patients living alone (OR = 1.63, p = 0.045) were all more likely to have PTSD. Older patients (OR = 1.65, p = 0.020), women (OR = 1.62, p = 0.018), those with a higher FCR score (OR = 5.02, p < 0.001), patients unsatisfied with their cancer management (OR = 2.36, p < 0.001), and those afraid to come to hospital due to COVID-19 (OR = 2.43, p < 0.001) all had a higher risk of anxiety. These results provide a greater understanding of the psychological consequences of the COVID-19 pandemic in cancer patients and highlight the need to better integrate psychosocial support in pandemic response measures in order to guide health systems.
癌症患者通常会经历心理困扰，在当前的新冠疫情期间，这种困扰可能会加剧。这项前瞻性研究旨在测量法国首次因新冠疫情实施封锁后癌症患者的创伤后应激障碍（PTSD）和焦虑情况，以及相关因素。接受门诊治疗或治疗后随访的癌症患者完成了一份问卷，该问卷除其他内容外，还测量了创伤后应激障碍（IES-R）、焦虑（状态-特质焦虑量表）和癌症复发恐惧（FCR）。在纳入研究的1097名患者中，分别有14.7%和30.5%患有创伤后应激障碍和焦虑症。因新冠病毒传播风险而害怕前往医院的患者（OR = 3.49，p < 0.001）、有负面封锁经历的患者（OR = 0.98，p < 0.001）、女性（OR = 1.97；p = 0.009）以及独居患者（OR = 1.63，p = 0.045）患创伤后应激障碍的可能性都更高。老年患者（OR = 1.65，p = 0.020）、女性（OR = 1.62，p = 0.018）、癌症复发恐惧得分较高的患者（OR = 5.02，p < 0.001）、对癌症治疗不满意的患者（OR = 2.36，p < 0.001）以及因新冠疫情而害怕前往医院的患者（OR = 2.43，p < 0.001）患焦虑症的风险都更高。这些结果让我们对新冠疫情给癌症患者带来的心理影响有了更深入的了解，并强调有必要在疫情应对措施中更好地融入社会心理支持，以指导卫生系统。
