Noor Research Center for Ophthalmic Epidemiology, Noor Eye Hospital, Tehran, Iran.
Noor Ophthalmology Research Center, Noor Eye Hospital, Tehran, Iran.
Sci Rep. 2022 May 11;12(1):7748. doi: 10.1038/s41598-022-11953-8.
To determine the repeatability of biometric measurements by dual Scheimpflug Devices with Integrated Optical Biometers and its agreement with partial coherence interferometry according to the axial length (AL), and the presence of cataracts. The present population-based cross-sectional study was conducted on the geriatric population in Tehran. For participants, imaging was performed by dual Scheimpflug Devices with Integrated Optical Biometers (Galilei G6) and partial coherence interferometry (IOL Master 500). All measurements were performed by one person. In both normal and cataractous eyes, the ICC values were above 0.99 for three measurements of AL, intraocular lens (IOL) power target, anterior chamber depth (ACD), central corneal thickness (CCT), flat and steep keratometry readings, and mean total corneal power (MTCP). The repeatability coefficient for the AL measurements was 0.003 and 0.002 in eyes with and without cataracts, respectively. The mean difference of AL between IOL Master 500 and Galilei G6 in normal and cataractous eyes was 0.015 and -0.003 mm, respectively. The 95% limits of agreement (LoA) of AL between these two devices were -0.09 to 0.12 mm in normal and -0.09 to 0.08 mm in cataractous eyes. The 95% LoA of ACD between the two devices was -0.13 to 0.36 mm and -0.10 to 0.31 mm in eyes without and with cataracts, respectively. The 95% LoA of steep K between the two devices was -0.63 to 0.32 and -1.04 to 0.89 diopter in normal and cataractous eyes, respectively. The results of the present study indicate the high repeatability of Galilei G6 in ocular biometric measurements. Galilei biometric measurements, had a very high agreement with the IOL Master 500.
评估双通道 Scheimpflug 设备与集成光学生物测量仪（Galilei G6）测量生物测量指标的重复性及其与轴向长度（AL）和白内障的部分相干干涉测量法（IOL Master 500）的一致性。本研究为基于人群的横断面研究，在德黑兰的老年人群中进行。对于参与者，通过双通道 Scheimpflug 设备与集成光学生物测量仪（Galilei G6）和部分相干干涉测量法（IOL Master 500）进行成像。所有测量均由一人进行。在正常眼和白内障眼中，AL、人工晶状体（IOL）目标屈光力、前房深度（ACD）、中央角膜厚度（CCT）、平坦和陡峭角膜曲率读数以及平均总角膜屈光力（MTCP）的三次测量的 ICC 值均高于 0.99。白内障眼和非白内障眼的 AL 测量重复性系数分别为 0.003 和 0.002。正常眼和白内障眼中，IOL Master 500 与 Galilei G6 之间的 AL 平均差值分别为 0.015 和 -0.003mm。这两种设备之间的 AL 95%一致性界限（LoA）在正常眼中为-0.09 至 0.12mm，在白内障眼中为-0.09 至 0.08mm。这两种设备之间的 ACD 的 95%LoA 在无白内障眼和有白内障眼中分别为-0.13 至 0.36mm 和-0.10 至 0.31mm。这两种设备之间的陡峭 K 的 95%LoA 在正常眼中和白内障眼中分别为-0.63 至 0.32 和-1.04 至 0.89 屈光度。本研究结果表明 Galilei G6 对眼部生物测量指标具有高度可重复性。Galilei 生物测量值与 IOL Master 500 非常吻合。
