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ACE2-enriched extracellular vesicles enhance infectivity of live SARS-CoV-2 virus.

作者信息

Tey Sze Keong, Lam Hoiyan, Wong Samuel Wan Ki, Zhao Hanjun, To Kelvin Kai-Wang, Yam Judy Wai Ping

机构信息

Department of Pathology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Pokfulam, People's Republic of China.

School of Biological Sciences, College of Science, Nanyang Technological University, Singapore, Singapore.

出版信息

J Extracell Vesicles. 2022 May;11(5):e12231. doi: 10.1002/jev2.12231.

DOI:10.1002/jev2.12231
PMID:35582880
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9115585/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c627/9115585/de8d2a42dc85/JEV2-11-e12231-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c627/9115585/97461e2b63dd/JEV2-11-e12231-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c627/9115585/de8d2a42dc85/JEV2-11-e12231-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c627/9115585/97461e2b63dd/JEV2-11-e12231-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c627/9115585/de8d2a42dc85/JEV2-11-e12231-g002.jpg

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Engineering Extracellular Vesicles Enriched with Palmitoylated ACE2 as COVID-19 Therapy.工程化富含棕榈酰化 ACE2 的细胞外囊泡作为 COVID-19 治疗方法。
Adv Mater. 2021 Dec;33(49):e2103471. doi: 10.1002/adma.202103471. Epub 2021 Oct 19.
2
Neutralization of SARS-CoV-2 pseudovirus using ACE2-engineered extracellular vesicles.使用工程化的ACE2细胞外囊泡中和严重急性呼吸综合征冠状病毒2(SARS-CoV-2)假病毒
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The impact of spike N501Y mutation on neutralizing activity and RBD binding of SARS-CoV-2 convalescent serum.
Viral Membrane-Targeting Amphipathic Helical Peptide-Based Fluorogenic Probes for the Analysis of Infectious Titers of Enveloped Viruses.
用于分析包膜病毒感染滴度的基于病毒膜靶向两亲性螺旋肽的荧光探针
Anal Chem. 2025 Mar 18;97(10):5480-5487. doi: 10.1021/acs.analchem.4c04852. Epub 2025 Jan 22.
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Circulating extracellular vesicles from severe COVID-19 patients induce lung inflammation.严重 COVID-19 患者的循环细胞外囊泡诱导肺部炎症。
mSphere. 2024 Nov 21;9(11):e0076424. doi: 10.1128/msphere.00764-24. Epub 2024 Oct 30.
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Feline coronavirus influences the biogenesis and composition of extracellular vesicles derived from CRFK cells.猫冠状病毒影响源自猫肾传代细胞(CRFK细胞)的细胞外囊泡的生物发生和组成。
Front Vet Sci. 2024 Jul 18;11:1388438. doi: 10.3389/fvets.2024.1388438. eCollection 2024.
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Int J Mol Sci. 2024 Feb 19;25(4):2415. doi: 10.3390/ijms25042415.
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