Operative Department, Faculty of Dentistry, Zagazig University, Zagazig, Egypt.
Operative Dentistry Department, Faculty of Dentistry, Mansoura University, Algomhoria St, Mansoura City, 35516, Egypt.
Sci Rep. 2022 Jun 15;12(1):9926. doi: 10.1038/s41598-022-13608-0.
To evaluate the remineralization potential of prepared tricalcium silicate (TCS) paste compared to silver diamine fluoride-potassium iodide (SDF-KI) and casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) on artificial enamel lesions. Thirty permanent sound molars were collected for the study. After cleaning, root cutting, and applying acid-resistant nail varnish, leaving a 4 × 4 mm buccal window, the teeth were subjected to demineralization process. The teeth were divided into three treatment groups (n = 10). In each group, the teeth were sectioned buccolingually to obtain two halves (30 self-control and 30 experimental halves). The self-control halves were subjected to cross-sectional microhardness (CSMH), energy-dispersive X-ray spectroscopy at 50, 100, and 150 µm from the external enamel surface, and micromorphological analysis at the superficial enamel surface. The experimental halves were subjected to the same tests after 30 days of remineralization. Three-way analysis of variance (ANOVA) outcomes showed no significant difference in CSMH after treatment among the three different groups at the different levels (p > 0.05). Meanwhile, three-way ANOVA outcomes showed a significant difference in calcium/ phosphate ratio after treatment among the three different groups at the different levels. (p < 0.05). The tricalcium silicate paste used in this study showed potential remineralization in subsurface enamel lesions.
评估硅酸三钙（TCS）糊剂相对于银胺氟化钾-碘化钾（SDF-KI）和酪蛋白磷酸肽-无定形磷酸钙（CPP-ACP）在人工釉质龋损再矿化中的潜力。收集了 30 颗恒磨牙用于研究。清洁、根切并涂上耐酸指甲油后，在颊侧留下一个 4 × 4 毫米的窗口，然后对牙齿进行脱矿处理。将牙齿分为三组（每组 n=10）。每组的牙齿均进行颊舌向切割，以获得两个半（30 个自身对照和 30 个实验半）。自身对照半进行横截面试硬度（CSMH）、距釉质表面 50、100 和 150 µm 的能量色散 X 射线光谱以及表面釉质微观形态分析。30 天后，实验半进行相同的测试。三因素方差分析（ANOVA）结果显示，在不同水平下，三种不同组间治疗后的 CSMH 无显著差异（p>0.05）。同时，三因素方差分析结果显示，在不同水平下，三种不同组间治疗后的钙/磷比值有显著差异。（p<0.05）。本研究中使用的硅酸三钙糊剂在釉下牙本质龋损中有潜在的再矿化作用。
