Al-Harbi L M, Darwish Mohamed S A
Chemistry Department, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah, 21589, Saudi Arabia.
Egyptian Petroleum Research Institute, 1 Ahmed El-Zomor Street, El Zohour Region, Nasr City, Cairo, 11727, Egypt.
Heliyon. 2022 Jun 6;8(6):e09654. doi: 10.1016/j.heliyon.2022.e09654. eCollection 2022 Jun.
Dual-functional iron oxide nanoparticles (IONPs), displaying self-heating and antibacterial effects are highly desired for biomedical application. This study involved the synthesis of functionalized IONPs coated with 3-aminopropyltriethoxysilane and polyethylene glycol via ultrasonic-assisted co-precipitation technique. The synthesized IONPs were then characterized by using Fourier-transform infrared spectroscopy, X-ray diffraction, dynamic light scattering, scanning electron microscopy, zeta potential, vibrating sample magnetometer and thermogravimetric analysis techniques. In addition, the effect of the synthesized IONPs on bacterial growth ( and ) was studied. The influence of magnetic field power, as well as the viscous carriers on the heating efficiency of the synthesized IONPs was investigated. The specific absorption rate values increased as the power increased and decreased with the increase in the carrier viscosity. These characteristics render the synthesized iron oxide nanoparticles synthesized in the present study suitable for biomedical application as hyperthermic agents.
具有自热和抗菌双重功能的氧化铁纳米颗粒（IONPs）在生物医学应用中备受青睐。本研究通过超声辅助共沉淀技术合成了包覆有3-氨丙基三乙氧基硅烷和聚乙二醇的功能化IONPs。然后，使用傅里叶变换红外光谱、X射线衍射、动态光散射、扫描电子显微镜、zeta电位、振动样品磁强计和热重分析技术对合成的IONPs进行了表征。此外，还研究了合成的IONPs对细菌生长（和）的影响。研究了磁场功率以及粘性载体对合成的IONPs加热效率的影响。比吸收率值随功率增加而增加，随载体粘度增加而降低。这些特性使得本研究中合成的氧化铁纳米颗粒适合作为热疗剂用于生物医学应用。
