Instituto de Investigaciones Químico Biológicas, Universidad Michoacana de San Nicolás de Hidalgo, Ciudad Universitaria, Morelia 58030, Michoacán, Mexico.
Centro Multidisciplinario de Estudios en Biotecnología, Facultad de Medicina Veterinaria y Zootecnia, Universidad Michoacana de San Nicolás de Hidalgo, Tarímbaro 58893, Michoacán, Mexico.
Molecules. 2022 Jun 20;27(12):3937. doi: 10.3390/molecules27123937.
Different ethnomedicinal studies have investigated the relationship between various phytochemicals as well as organic extracts and their bioactive aspects. Studies on biological effects are attributed to secondary metabolites such as alkaloids, phenolic compounds, and terpenes. Since there have been no reviews in the literature on the traditional, phytochemical, and ethnomedicinal uses of the genus so far, this article systematically reviews 141 published studies that analyze the associations between secondary metabolites present in organic extracts and their beneficial effects. Most studies found associations between individual secondary metabolites and beneficial effects such as anticancer activity, antibacterial, antioxidant activity, snake anti-venom and anti-inflammatory activity. The aim of this review was to analyze studies carried out in the period 2005-2021 to update the existing knowledge on different species of the genus for ethnomedicinal uses, as well as pharmacological aspects and therapeutic uses.
不同的民族医学研究已经调查了各种植物化学物质以及有机提取物及其生物活性方面之间的关系。对生物效应的研究归因于生物碱、酚类化合物和萜类等次生代谢物。由于迄今为止,文献中尚无关于该属的传统、植物化学和民族医学用途的综述,本文系统地综述了 141 篇分析有机提取物中存在的次生代谢物及其有益作用之间关联的已发表研究。大多数研究发现,个别次生代谢物与有益作用之间存在关联,如抗癌活性、抗菌活性、抗氧化活性、抗蛇毒和抗炎活性。本综述的目的是分析 2005-2021 年期间进行的研究,以更新关于该属不同物种的民族医学用途、药理学方面和治疗用途的现有知识。