含咖啡因口香糖改善受睡眠剥夺影响的认知功能的有效性。
The effectiveness of caffeinated chewing gum in ameliorating cognitive functions affected by sleep deprivation.
作者信息
Moradi AliReza, Ghahremaninejad Farrokh, Hoseini Ehsan, Talebi Mohammad Naseh, Lohrasbi Soroush, Farahimanesh Sharareh, Nami Mohammad, Khazaei Habibollah, Kazemi Kamran, Mohammadi Mohammad
机构信息
Kharazmi University, Department of Clinical Psychology, Faculty of Psychology & Educational Sciences - Tehran - Iran.
Institute for Cognitive Science Studies, Tehran - Iran.
出版信息
Sleep Sci. 2022 Apr-Jun;15(2):216-223. doi: 10.5935/1984-0063.20220044.
OBJECTIVES
This investigation aimed to compare caffeinated gums with two different dosages of caffeine (200mg vs. 300mg) by assessing their effectiveness on the improvement of cognitive functions among Iranian individuals voluntarily suffering from 30 hours of sleep deprivation.
MATERIAL AND METHODS
Thirty-four healthy male volunteers with ages from 28 to 35 years old were randomly assigned to either 200 or 300mg caffeine intake. Each participant completed CANTAB subtests to assess their core cognitive functions including MOT, RTI, RVP, and SWM before and after sleep deprivation, as well as after being treated with caffeinated gum.
RESULTS
The 300mg caffeine intake group indicated higher levels of enhancement of core cognitive functions compared with those in the 200mg caffeine intake group.
CONCLUSION
This study suggests that the dose of 300mg of caffeine could effectively enhance the cognitive functions of Iranian individuals suffering from sleep deprivation.
目的
本研究旨在通过评估含不同剂量咖啡因（200毫克与300毫克）的口香糖对自愿经历30小时睡眠剥夺的伊朗人认知功能改善的有效性，对其进行比较。
材料与方法
34名年龄在28至35岁之间的健康男性志愿者被随机分配到摄入200毫克或300毫克咖啡因组。每位参与者在睡眠剥夺前后以及服用含咖啡因口香糖后，完成剑桥神经心理测试自动化成套系统（CANTAB）子测试，以评估其核心认知功能，包括运动反应时（MOT）、反应时抑制（RTI）、逆向视空间工作记忆（RVP）和空间广度记忆（SWM）。
结果
与摄入200毫克咖啡因组相比，摄入300毫克咖啡因组的核心认知功能增强水平更高。
结论
本研究表明，300毫克咖啡因剂量可有效增强遭受睡眠剥夺的伊朗人的认知功能。
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