Department of Food Biotechnology, Faculty of Health Science, Medical University of Białystok, Szpitalna 37 Street, 15-295 Białystok, Poland.
Department of Bromatology, Faculty of Pharmacy with the Division of Laboratory Medicine, Medical University of Białystok, Mickiewicza 2D Street, 15-222 Białystok, Poland.
Nutrients. 2022 Jun 28;14(13):2688. doi: 10.3390/nu14132688.
Abnormal metabolism of substances in the body can result in metabolic disorders which include obesity, cardiovascular diseases, diabetes, hypertension, chronic kidney disease, liver disease, or cancer. Foods rich in antioxidants can help to prevent and treat various types of disorders. Chokeberry fruits are rich in polyphenols, especially cyanidins, and therefore, can show a beneficial health effect. The aim of this study was to summarize and systematize reports about the effects of chokeberry on various metabolic parameters. Studies from 2000 to 2021, published in the PubMed and Google Scholar databases, were reviewed. The review of studies shows that chokeberry may have a positive effect in dyslipidemia and hypertension and may increase the body's antioxidant defense mechanisms. The anti-inflammatory effect, in turn, may translate into a reduction in the risk of metabolic disorders over a longer period of use. Changes in glucose levels were reported by studies in which the intervention lasted more than 10 weeks in patients with carbohydrate metabolism disorders. The effects of protecting the liver, inhibiting platelet aggregation, lowering uric acid levels, and having a protective effect on the kidneys require additional confirmation in human clinical trials. Consumption of chokeberry fruit did not impact on anthropometric measurements; however, it seems that chokeberry fruit can be recommended in many metabolic disorders due to the richness of bioactive ingredients.
体内物质的异常代谢会导致代谢紊乱，包括肥胖、心血管疾病、糖尿病、高血压、慢性肾病、肝病或癌症。富含抗氧化剂的食物有助于预防和治疗各种类型的疾病。沙棘果实富含多酚，尤其是花青素，因此具有有益的健康作用。本研究旨在总结和系统化沙棘对各种代谢参数影响的报告。回顾了 2000 年至 2021 年在 PubMed 和 Google Scholar 数据库中发表的研究。研究综述表明，沙棘可能对血脂异常和高血压有积极影响，并可能增加机体的抗氧化防御机制。反过来，抗炎作用可能会在更长的使用时间内降低代谢紊乱的风险。在干预时间超过 10 周的碳水化合物代谢紊乱患者的研究中，报告了血糖水平的变化。保护肝脏、抑制血小板聚集、降低尿酸水平以及对肾脏的保护作用需要在人体临床试验中进一步证实。沙棘果实的摄入对人体测量指标没有影响；然而，由于富含生物活性成分，沙棘果实似乎可以在许多代谢紊乱中推荐使用。
