Chen Hongbo, Hou Kai, Yu Jing, Wang Le, Chen Xue
Department of Plastic and Cosmetic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Department of Nephrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Front Oncol. 2022 Jun 28;12:928797. doi: 10.3389/fonc.2022.928797. eCollection 2022.
Melanoma is a cutaneous carcinoma, and its incidence is rapidly increasing with every year. The treatment options for melanoma have been comprehensively studied. Conventional treatment methods (e.g., radiotherapy, chemotherapy and photodynamic therapy) with surgical removal inevitably cause serious complications; moreover, resistance is common. Nanoparticles (NPs) combined with conventional methods are new and promising options to treat melanoma, and many combinations have been achieving good success. Due to their physical and biological features, NPs can help target intended melanoma cells more efficiently with less damage. This creates new hope for a better treatment strategy for melanoma with minimum damage and maximum efficacy.
黑色素瘤是一种皮肤癌，其发病率逐年迅速上升。黑色素瘤的治疗方案已得到全面研究。常规治疗方法（如放疗、化疗和光动力疗法）结合手术切除不可避免地会引发严重并发症；此外，耐药现象很常见。纳米颗粒（NPs）与传统方法相结合是治疗黑色素瘤的新的且有前景的选择，许多组合已取得良好成效。由于其物理和生物学特性，纳米颗粒能够以更小的损伤更有效地靶向目标黑色素瘤细胞。这为以最小损伤和最大疗效治疗黑色素瘤的更好治疗策略带来了新希望。
