Pan Juan, Zhou Kai, Wang Jing, Zheng Yufen, Yu Die, Kang Haixin, Zhang Yanjie, Peng Shuotao, Tung Tao-Hsin, Shen Bo
Department of Clinical Laboratory, Taizhou Hospital, Zhejiang University, Linhai 317000, China.
Department of Clinical Laboratory, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai 317000, China.
Brain Sci. 2022 Jul 18;12(7):939. doi: 10.3390/brainsci12070939.
According to previous studies, mental status in 1-year COVID-19 survivors might range from 6-43%. Longer-term psychological consequences in recovered COVID-19 subjects are unknown, so we analyzed longer-term quality of life and mental status in recovered COVID-19 subjects at 2 years after infection. Among 144 recovered COVID-19 subjects in the Taizhou region, 73 and 45 completed face-to-face follow-ups at the first year and second year after infection, respectively, with a 61.7% follow-up rate. The questionnaire, which was administered at both follow-ups, included questions about quality of life, psychological health, and post-traumatic stress disorder (PTSD). The Mann-Whitney U test was used to the differences of each scale between the first and second year. Among the 45 people who completed both follow-up visits, the incidence of psychological problems was 4.4% (2/45) in the first year, and no new psychological abnormalities were observed in the second year. Quality of life improved, while the General Health Questionnaire (GHQ-12) and Impact of Event Scale-Revised (IES-R) scores did not improve over time. The incidence of mental disorders was lower than those in previous studies. Multidisciplinary management for COVID-19 in this study hospital may have reduced the frequency to a certain extent. However, among those with mental health problems, such problems may exist for a long time, and long-term attention should be given to the psychological status of recovered COVID-19 subjects.
根据先前的研究，新冠病毒感染1年后幸存者的精神状态问题发生率可能在6%-43%之间。新冠病毒感染康复者的长期心理后果尚不清楚，因此我们分析了新冠病毒感染康复者在感染2年后的长期生活质量和精神状态。在台州地区的144名新冠病毒感染康复者中，分别有73名和45名在感染后的第一年和第二年完成了面对面随访，随访率为61.7%。两次随访均使用了包含生活质量、心理健康和创伤后应激障碍（PTSD）相关问题的问卷。采用曼-惠特尼U检验分析第一年和第二年各量表之间的差异。在完成两次随访的45人中，第一年心理问题发生率为4.4%（2/45），第二年未观察到新的心理异常。生活质量有所改善，但一般健康问卷（GHQ-12）和事件影响量表修订版（IES-R）得分并未随时间改善。精神障碍的发生率低于先前研究中的发生率。本研究医院对新冠病毒感染的多学科管理可能在一定程度上降低了发生率。然而，在有心理健康问题的人群中，此类问题可能会长期存在，应长期关注新冠病毒感染康复者的心理状态。
