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益生菌的生物解毒与保护特性

Biodetoxification and Protective Properties of Probiotics.

作者信息

Pop Oana Lelia, Suharoschi Ramona, Gabbianelli Rosita

机构信息

Department of Food Science, University of Agricultural Sciences and Veterinary Medicine, 400372 Cluj-Napoca, Romania.

Molecular Nutrition and Proteomics Laboratory, Institute of Life Sciences, University of Agricultural Sciences and Veterinary Medicine, 400372 Cluj-Napoca, Romania.

出版信息

Microorganisms. 2022 Jun 23;10(7):1278. doi: 10.3390/microorganisms10071278.

DOI:10.3390/microorganisms10071278
PMID:35888997
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9319832/
Abstract

Probiotic consumption is recognized as being generally safe and correlates with multiple and valuable health benefits. However, the mechanism by which it helps detoxify the body and its anti-carcinogenic and antimutagenic potential is less discussed. A widely known fact is that globalization and mass food production/cultivation make it impossible to keep all possible risks under control. Scientists associate the multitude of diseases in the days when we live with these risks that threaten the population's safety in terms of food. This review aims to explore whether the use of probiotics may be a safe, economically viable, and versatile tool in biodetoxification despite the numerous risks associated with food and the limited possibility to evaluate the contaminants. Based on scientific data, this paper focuses on the aspects mentioned above and demonstrates the probiotics' possible risks, as well as their anti-carcinogenic and antimutagenic potential. After reviewing the probiotic capacity to react with pathogens, fungi infection, mycotoxins, acrylamide toxicity, benzopyrene, and heavy metals, we can conclude that the specific probiotic strain and probiotic combinations bring significant health outcomes. Furthermore, the biodetoxification maximization process can be performed using probiotic-bioactive compound association.

摘要

食用益生菌被认为总体上是安全的,并且与多种有价值的健康益处相关。然而,关于益生菌帮助身体解毒的机制及其抗癌和抗诱变潜力的讨论较少。一个广为人知的事实是,全球化和大规模食品生产/种植使得无法控制所有可能的风险。科学家们将我们生活时代的众多疾病与这些威胁食品安全的风险联系起来。本综述旨在探讨尽管存在与食品相关的众多风险以及评估污染物的可能性有限,但使用益生菌是否可能成为生物解毒中一种安全、经济可行且通用的工具。基于科学数据,本文聚焦于上述方面,展示了益生菌可能存在的风险及其抗癌和抗诱变潜力。在回顾了益生菌与病原体、真菌感染、霉菌毒素、丙烯酰胺毒性、苯并芘和重金属反应的能力后,我们可以得出结论,特定的益生菌菌株和益生菌组合能带来显著的健康效益。此外,可通过益生菌 - 生物活性化合物联合来实现生物解毒最大化过程。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1719/9319832/d271dc7b8bb0/microorganisms-10-01278-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1719/9319832/2c17e1cc8824/microorganisms-10-01278-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1719/9319832/97e936316483/microorganisms-10-01278-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1719/9319832/d271dc7b8bb0/microorganisms-10-01278-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1719/9319832/2c17e1cc8824/microorganisms-10-01278-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1719/9319832/97e936316483/microorganisms-10-01278-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1719/9319832/d271dc7b8bb0/microorganisms-10-01278-g003.jpg

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Probiotic Supplementation Improved Capecitabine Protective Effect against Gastric Cancer Growth in Male BALB/c Mice.补充益生菌可增强卡培他滨对雄性BALB/c小鼠胃癌生长的保护作用。
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Assessing the Effectiveness of Fermented Banana Peel Extracts for the Biosorption and Removal of Cadmium to Mitigate Inflammation and Oxidative Stress.评估发酵香蕉皮提取物对镉的生物吸附和去除效果以减轻炎症和氧化应激
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