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维生素 D、神经反馈和神经反馈联合维生素 D 补充治疗对注意缺陷多动障碍儿童的比较。

Comparison of Vitamin D, Neurofeedback, and Neurofeedback Combined with Vitamin D Supplementation in Children with Attention-Deficit/Hyperactivity Disorder.

机构信息

School of Medicine and Surgery, University of Milano-Bicocca, Milano, Italy.

Department of Counseling, Imam Reza International University, Mashhad, Iran.

出版信息

Arch Iran Med. 2022 May 1;25(5):285-393. doi: 10.34172/aim.2022.47.

DOI:10.34172/aim.2022.47
PMID:35943003
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11904292/
Abstract

BACKGROUND

Nowadays, some treatments such as neurofeedback and Vitamin D Supplementation are of great importance in the treatment of attention-deficit/hyperactivity disorder (ADHD). To determine the efficacy of the combined treatment, the present trial was conducted to investigate the effectiveness of each one of them with combined neurofeedback and vitamin D supplementation in the reduction of ADHD symptom in children suffering from this disorder.

METHODS

In this study from March 2020 to June 2020, we enrolled a total of 120 patients (6-15 years old) who were referred to the Mehr psychiatric hospital (affiliated to Lorestan University of Medical Sciences). Patients were then randomly categorized into three experimental groups and one control group. The first, the second, and the third experimental groups consumed vitamin D pearl, neurofeedback combined with vitamin D, and neurofeedback for 12 weeks, respectively. The control group was given no treatment. Vitamin D serum level was evaluated at baseline, 4, 8, and 12 weeks in all participants. For data collection, the Parent Attention-Deficit/Hyperactivity Disorder Rating Scale-IV (ADHD-RS-IV) was applied. The obtained information was analyzed using repeated measure variance analysis.

RESULTS

The mean scores were significantly different across the groups. Repeated measure variance analysis showed that the mean score was lower in the combined group in comparison with the other three groups (<0.05).

CONCLUSION

Combined treatment could be considered as more effective compared to separate treatments. In addition, in this study, by applying the combined intervention, the duration of treatment decreased significantly.

摘要

背景

如今,神经反馈和维生素 D 补充等一些治疗方法在治疗注意力缺陷/多动障碍(ADHD)方面非常重要。为了确定联合治疗的疗效,本试验旨在研究联合神经反馈和维生素 D 补充治疗对患有这种疾病的儿童 ADHD 症状的减轻作用。

方法

在这项 2020 年 3 月至 6 月进行的研究中,我们共招募了 120 名(6-15 岁)患者,他们被转诊到 Mehr 精神病院(隶属于洛雷斯坦医科大学)。然后,患者被随机分为三组实验组和一组对照组。第一、第二和第三实验组分别服用维生素 D 丸、神经反馈联合维生素 D 和神经反馈治疗 12 周。对照组不进行任何治疗。所有参与者均在基线、4、8 和 12 周评估维生素 D 血清水平。为了收集数据,我们使用了父母注意缺陷/多动障碍评定量表-IV(ADHD-RS-IV)。使用重复测量方差分析对获得的信息进行分析。

结果

各组之间的平均得分存在显著差异。重复测量方差分析显示,联合组的平均得分明显低于其他三组(<0.05)。

结论

与单独治疗相比,联合治疗可能更为有效。此外,在这项研究中,通过应用联合干预,治疗时间显著缩短。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b6c/11904292/828b32827cd8/aim-25-285-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b6c/11904292/cc06b639ea06/aim-25-285-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b6c/11904292/68cc0b7fbe87/aim-25-285-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b6c/11904292/828b32827cd8/aim-25-285-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b6c/11904292/cc06b639ea06/aim-25-285-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b6c/11904292/68cc0b7fbe87/aim-25-285-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b6c/11904292/828b32827cd8/aim-25-285-g003.jpg

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