Zhang Ting, Wang Wen, Liu Jia, Wang Liqiang, Tang Yujin, Wang Kuaishe
School of Metallurgical Engineering, Xi'an University of Architecture and Technology, Xi'an, China.
Department of Orthopaedics, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, Guangxi, China.
Front Bioeng Biotechnol. 2022 Aug 16;10:953344. doi: 10.3389/fbioe.2022.953344. eCollection 2022.
Magnesium (Mg) and Mg alloys are considered as potential candidates for biomedical applications because of their high specific strength, low density, and elastic modulus, degradability, good biocompatibility and biomechanical compatibility. However, the rapid corrosion rate of Mg alloys results in premature loss of mechanical integrity, limiting their clinical application in load-bearing parts. Besides, the low strength of Mg alloys restricts their further application. Thus, it is essential to understand the characteristics and influencing factors of mechanical and corrosion behavior, as well as the methods to improve the mechanical performances and corrosion resistance of Mg alloys. This paper reviews the recent progress in elucidating the corrosion mechanism, optimizing the composition, and microstructure, enhancing the mechanical performances, and controlling the degradation rate of Mg alloys. In particular, the research progress of surface modification technology of Mg alloys is emphasized. Finally, the development direction of biomedical Mg alloys in the future is prospected.
镁（Mg）及其合金因其高比强度、低密度、弹性模量、可降解性、良好的生物相容性和生物力学相容性，被视为生物医学应用的潜在候选材料。然而，镁合金的快速腐蚀速率导致其过早丧失机械完整性，限制了它们在承重部件中的临床应用。此外，镁合金的低强度也限制了其进一步应用。因此，了解镁合金力学和腐蚀行为的特征及影响因素，以及提高其力学性能和耐腐蚀性的方法至关重要。本文综述了近年来在阐明镁合金腐蚀机理、优化成分和微观结构、提高力学性能以及控制降解速率方面的研究进展。特别强调了镁合金表面改性技术的研究进展。最后，展望了生物医学镁合金未来的发展方向。
