Bai Yu, Pei Yigang, Liu Weiyin Vivian, Liu Wenguang, Xie Simin, Wang Xiao, Zhong Linhui, Chen Juan, Zhang Lijuan, Masokano Ismail Bilal, Li Wenzheng
Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China.
J Magn Reson Imaging. 2023 Apr;57(4):1156-1171. doi: 10.1002/jmri.28382. Epub 2022 Aug 27.
Diffusion-weighted imaging (DWI) is a useful technique to detect pancreatic lesion. In DWIs, field-of-view optimized and constrained undistorted single-shot (FOCUS) can improve the spatial resolution and multiplexed sensitivity-encoding (MUSE) can gain a high signal-to-noise ratio (SNR). Based on the advantage of FOCUS and MUSE, a new DWI sequence-named FOCUS-MUSE DWI (FOCUS combined with MUSE)-was developed to delineate the pancreas.
To investigate the reliability of FOCUS-MUSE DWI compared to FOCUS, MUSE and single-shot (SS) DWI via the systematical evaluation of the apparent diffusion coefficient (ADC) measurements, SNR and image quality.
Prospective.
A total of 33 healthy volunteers and 9 patients with pancreatic lesion.
FIELD STRENGTH/SEQUENCE: A 3.0 T scanner. FOCUS-MUSE DWI, FOCUS DWI, MUSE DWI, SS DWI.
For volunteers, ADC and SNR were measured by two readers in the pancreatic head, body, and tail. For all subjects, the diagnostic image quality score was assessed by three other readers on above four DWIs.
Paired-sample T-test, intraclass correlation (ICC), Bland-Altman method, Friedman test, Dunn-Bonferroni post hoc test and kappa coefficient. A significance level of 0.05 was used.
FOCUS-MUSE DWI had the best intersession repeatability of ADC measurements (head: 59.53, body: 101.64, tail: 42.30) among the four DWIs, and also maintained the significantly highest SNR (reader 1 [head: 19.68 ± 3.23, body: 23.42 ± 5.00, tail: 28.85 ± 4.96], reader 2 [head: 19.93 ± 3.52, body: 23.02 ± 5.69, tail: 29.77 ± 6.33]) except for MUSE DWI. Furthermore, it significantly achieved better image quality in volunteers (median value: 4 score) and 9 patients (most in 4 score).
FOCUS-MUSE DWI improved the reliability of pancreatic images with the most stable ADC measurement, best image quality score and sufficient SNR among four DWIs.
2 TECHNICAL EFFICACY: Stage 2.
扩散加权成像（DWI）是检测胰腺病变的一种有用技术。在DWI中，视野优化约束无失真单次激发（FOCUS）可提高空间分辨率，而多通道灵敏度编码（MUSE）可获得高信噪比（SNR）。基于FOCUS和MUSE的优势，开发了一种名为FOCUS-MUSE DWI（FOCUS与MUSE相结合）的新DWI序列来描绘胰腺。
通过对表观扩散系数（ADC）测量值、SNR和图像质量的系统评估，研究FOCUS-MUSE DWI与FOCUS、MUSE和单次激发（SS）DWI相比的可靠性。
前瞻性研究。
共33名健康志愿者和9名胰腺病变患者。
场强/序列：3.0 T扫描仪。FOCUS-MUSE DWI、FOCUS DWI、MUSE DWI、SS DWI。
对于志愿者，由两名阅片者在胰头、胰体和胰尾测量ADC和SNR。对于所有受试者，由另外三名阅片者对上述四种DWI评估诊断图像质量评分。
配对样本t检验、组内相关系数（ICC）、Bland-Altman法、Friedman检验、Dunn-Bonferroni事后检验和kappa系数。显著性水平设定为0.05。
在四种DWI中，FOCUS-MUSE DWI的ADC测量值具有最佳的组间重复性（胰头：59.53，胰体：101.64，胰尾：42.30），并且除MUSE DWI外，还保持了显著最高的SNR（阅片者1[胰头：19.68±3.23，胰体：23.42±5.00，胰尾：28.85±4.96]，阅片者2[胰头：19.93±3.52，胰体：23.02±5.69，胰尾：29.77±6.33]）。此外，它在志愿者（中位数：4分）和9名患者（多数为4分）中显著获得了更好的图像质量。
FOCUS-MUSE DWI在四种DWI中具有最稳定的ADC测量值、最佳的图像质量评分和足够的SNR，提高了胰腺图像的可靠性。
2级 技术效能：2级
