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[具体物质]提取物对[相关指标]的影响：一项[研究类型]研究。 （注：原文中部分内容缺失，翻译只能根据现有内容尽量完善表达）

Effect of and extracts on and : An study.

作者信息

Akya Alisha, Chegene Lorestani Roya, Zhaleh Hossein, Nemati Zargaran Fatemeh, Ghadiri Keyghobad, Rostamian Mosayeb

机构信息

Infectious Diseases Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah 6714415333, Iran.

Substance Abuse Prevention Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah 6714415333, Iran.

出版信息

Chin Herb Med. 2020 Mar 5;12(2):171-177. doi: 10.1016/j.chmed.2019.12.006. eCollection 2020 Apr.

DOI:10.1016/j.chmed.2019.12.006
PMID:36119795
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9476805/
Abstract

OBJECTIVE

Current therapy strategies of leishmaniasis have some problems such as high cost, toxicity and side effects. Plant extracts can be a source of drugs to control leishmaniasis. In this study, the effect of hydroalcoholic and chloroformic extracts of , and on and was studied.

METHODS

The plant samples were collected from west of Iran and their extracts were prepared. Anti-promastigote activity assay of all extracts was done using tetrazolium-dye assay.

RESULTS

Only high concentrations of and were able to inhibit , while both high and low concentrations of had antileishmanial effect. No difference was observed between hydroalcoholic with chloroformic extract of each plant.

CONCLUSION

Altogether, the results revealed the antileishmanial activity of extracts against and , indicating its potential as an antileishmanial agent.

摘要

目的

利什曼病目前的治疗策略存在一些问题，如成本高、毒性和副作用。植物提取物可能是控制利什曼病的药物来源。本研究考察了[植物名称1]、[植物名称2]和[植物名称3]的水醇提取物和氯仿提取物对[利什曼原虫种类1]和[利什曼原虫种类2]的作用。

方法

从伊朗西部采集植物样本并制备提取物。所有提取物的抗前鞭毛体活性测定采用四唑染料法。

结果

只有高浓度的[植物名称1]和[植物名称2]能够抑制[利什曼原虫种类1]，而[植物名称3]的高浓度和低浓度均有抗利什曼原虫作用。每种植物的水醇提取物和氯仿提取物之间未观察到差异。

结论

总体而言，结果揭示了[植物名称1]、[植物名称2]和[植物名称3]提取物对[利什曼原虫种类1]和[利什曼原虫种类2]的抗利什曼原虫活性，表明其作为抗利什曼原虫剂的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c016/9476805/3de5a0ad9802/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c016/9476805/2da3c15c7492/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c016/9476805/ceaa1e4adc76/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c016/9476805/e0b5e4d6eedf/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c016/9476805/1e105ac257cd/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c016/9476805/3de5a0ad9802/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c016/9476805/2da3c15c7492/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c016/9476805/ceaa1e4adc76/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c016/9476805/e0b5e4d6eedf/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c016/9476805/1e105ac257cd/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c016/9476805/3de5a0ad9802/gr5.jpg

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