Physikalisch-Technische Bundesanstalt (PTB), Braunschweig, Germany.
University of Rome Tor Vergata, Industrial Engineering Dept., Rome, Italy.
Phys Med Biol. 2022 Oct 14;67(20). doi: 10.1088/1361-6560/ac950b.
. The aim of the presented study is to evaluate the dose response of the PTB's secondary standard system, which is based on alanine and electron spin resonance (ESR) spectroscopy measurement, in ultra-high-pulse-dose-rate (UHPDR) electron beams.. The alanine dosimeter system was evaluated in the PTB's UHPDR electron beams (20 MeV) in a range of 0.15-6.2 Gy per pulse. The relationship between the obtained absorbed dose to water per pulse and the in-beamline charge measurement of the electron pulses acquired using an integrating current transformer (ICT) was evaluated. Monte Carlo simulations were used to determine the beam quality conversion and correction factors required to perform alanine dosimetry.. The beam quality conversion factor from the reference qualityCo to 20 MeV obtained by Monte Carlo simulation, 1.010(1), was found to be within the standard uncertainty of the consensus value, 1.014(5). The dose-to-water relative standard uncertainty was determined to be 0.68% in PTB's UHPDR electron beams.. In this investigation, the dose-response of the PTB's alanine dosimeter system was evaluated in a range of dose per pulse between 0.15 Gy and 6.2 Gy and no evidence of dose-response dependency of the PTB's secondary standard system based on alanine was observed. The alanine/ESR system was shown to be a precise dosimetry system for evaluating absorbed dose to water in UHPDR electron beams.
. 本研究旨在评估基于丙氨酸和电子自旋共振（ESR）光谱测量的 PTB 次级标准系统在超高脉冲剂量率（UHPDR）电子束中的剂量响应。. 在 20 MeV 的 PTB UHPDR 电子束中，对丙氨酸剂量计系统进行了评估，剂量范围为 0.15-6.2 Gy/脉冲。评估了通过积分电流互感器（ICT）获取的电子脉冲的在线电荷量与每个脉冲获得的水吸收剂量之间的关系。使用蒙特卡罗模拟确定了进行丙氨酸剂量测量所需的束质转换和校正因子。. 通过蒙特卡罗模拟获得的从参考束质 Co 到 20 MeV 的束质转换因子为 1.010(1)，在共识值的标准不确定度范围内，为 1.014(5)。在 PTB 的 UHPDR 电子束中，水吸收剂量的相对标准不确定度确定为 0.68%。. 在本研究中，在 0.15 Gy 和 6.2 Gy 的剂量范围内评估了 PTB 丙氨酸剂量计系统的剂量响应，未观察到基于丙氨酸的 PTB 次级标准系统的剂量响应依赖性。证明了丙氨酸/ESR 系统是一种用于评估 UHPDR 电子束中水吸收剂量的精确剂量测量系统。
