• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

纳米技术与纳米材料在癌症诊断与治疗中的应用:综述

The Application of Nanotechnology and Nanomaterials in Cancer Diagnosis and Treatment: A Review.

作者信息

Kher Chinmay, Kumar Sunil

机构信息

Department of Medicine, Jawaharlal Nehru Medical College, Wardha, IND.

出版信息

Cureus. 2022 Sep 11;14(9):e29059. doi: 10.7759/cureus.29059. eCollection 2022 Sep.

DOI:10.7759/cureus.29059
PMID:36259014
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9564559/
Abstract

Cancer is one of the deadliest diseases worldwide in present times, with its incidence on a tremendous rise. It is caused by uncontrolled cell growth. Cancer therapies have advanced substantially, but there is a need for improvement in specificity and fear of systemic toxicity. Early detection is critical in improving patients' prognosis and quality of life, and recent advancements in technology, especially in dealing with biomaterials, have aided in that surge. Nanotechnology possesses the key to solving many of the downsides of traditional pharmaceutical formulations. Indeed, significant progress has been made in using customized nanomaterials for cancer diagnosis and treatment with high specificity, sensitivity, and efficacy. Nanotechnology is the integration of nanoscience into medicine by the use of nanoparticles. The advent of nanoscience in cancer diagnosis and treatment will help clinicians better assess and manage patients and improve the healthcare system and services. This review article gives an account of the clinical applications of nanoscience in the modern management of cancer, the different modalities of nanotechnology used, and the limitations and possible side effects of this new tool.

摘要

癌症是当今世界上最致命的疾病之一,其发病率正在急剧上升。它是由细胞不受控制的生长引起的。癌症治疗已经取得了很大进展,但在特异性方面仍有改进的必要,且存在对全身毒性的担忧。早期检测对于改善患者的预后和生活质量至关重要,而最近的技术进步,尤其是在生物材料处理方面的进步,有助于实现这一飞跃。纳米技术拥有解决传统药物制剂许多缺点的关键。事实上,在使用定制纳米材料进行癌症诊断和治疗方面已经取得了重大进展,具有高特异性、敏感性和疗效。纳米技术是通过使用纳米颗粒将纳米科学融入医学。纳米科学在癌症诊断和治疗中的出现将有助于临床医生更好地评估和管理患者,并改善医疗保健系统和服务。这篇综述文章阐述了纳米科学在现代癌症管理中的临床应用、所使用的不同纳米技术模式以及这种新工具的局限性和可能的副作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f8e/9564559/c344db5a518f/cureus-0014-00000029059-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f8e/9564559/c344db5a518f/cureus-0014-00000029059-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f8e/9564559/c344db5a518f/cureus-0014-00000029059-i01.jpg

相似文献

1
The Application of Nanotechnology and Nanomaterials in Cancer Diagnosis and Treatment: A Review.纳米技术与纳米材料在癌症诊断与治疗中的应用:综述
Cureus. 2022 Sep 11;14(9):e29059. doi: 10.7759/cureus.29059. eCollection 2022 Sep.
2
The Emergence of Nanotechnology in the Prognosis and Treatment of Myocardial Infarctions.纳米技术在心肌梗死预后及治疗中的出现。
Recent Pat Nanotechnol. 2025;19(1):35-55. doi: 10.2174/1872210517666230721123453.
3
Nanotechnology: an evidence-based analysis.纳米技术:基于证据的分析。
Ont Health Technol Assess Ser. 2006;6(19):1-43. Epub 2006 Nov 1.
4
The History of Nanoscience and Nanotechnology: From Chemical-Physical Applications to Nanomedicine.纳米科学与纳米技术的历史:从化学物理应用到纳米医学。
Molecules. 2019 Dec 27;25(1):112. doi: 10.3390/molecules25010112.
5
Emerging Applications of Nanotechnology in Healthcare Systems: Grand Challenges and Perspectives.纳米技术在医疗保健系统中的新兴应用:重大挑战与展望
Pharmaceuticals (Basel). 2021 Jul 21;14(8):707. doi: 10.3390/ph14080707.
6
Theranostics Aspects of Various Nanoparticles in Veterinary Medicine.兽医医学中各种纳米粒子的治疗学方面。
Int J Mol Sci. 2018 Oct 24;19(11):3299. doi: 10.3390/ijms19113299.
7
The Clinical Translation of Organic Nanomaterials for Cancer Therapy: A Focus on Polymeric Nanoparticles, Micelles, Liposomes and Exosomes.有机纳米材料在癌症治疗中的临床转化:聚焦于聚合物纳米粒子、胶束、脂质体和外泌体。
Curr Med Chem. 2018;25(34):4224-4268. doi: 10.2174/0929867324666170830113755.
8
Nanomedicine in cardiovascular therapy: recent advancements.纳米医学在心血管治疗中的应用:最新进展
Expert Rev Cardiovasc Ther. 2012 Jun;10(6):805-15. doi: 10.1586/erc.12.41.
9
Nanoparticles Mediated Target-specific Drug Delivery in Prostate Cancer: An In-depth Review.纳米颗粒介导的前列腺癌靶向药物递送:深入综述。
Curr Med Chem. 2022;29(24):4170-4184. doi: 10.2174/0929867329666211221112312.
10
Nanomedicine and its applications to the treatment of prostate cancer.纳米医学及其在前列腺癌治疗中的应用。
Ann Pharm Fr. 2014 Sep;72(5):303-16. doi: 10.1016/j.pharma.2014.04.006. Epub 2014 Jun 2.

引用本文的文献

1
Current Trends and Advances in Nanoplatforms-Based Imaging for Cancer Diagnosis.基于纳米平台的癌症诊断成像的当前趋势与进展
Indian J Microbiol. 2025 Mar;65(1):137-176. doi: 10.1007/s12088-024-01373-9. Epub 2024 Aug 9.
2
The Role of Ion Channels in Cervical Cancer Progression: From Molecular Biomarkers to Diagnostic and Therapeutic Innovations.离子通道在宫颈癌进展中的作用:从分子生物标志物到诊断与治疗创新
Cancers (Basel). 2025 May 1;17(9):1538. doi: 10.3390/cancers17091538.
3
Innovative laboratory techniques shaping cancer diagnosis and treatment in developing countries.

本文引用的文献

1
Application of Nanotechnology in Cancer Diagnosis and Therapy - A Mini-Review.纳米技术在癌症诊断与治疗中的应用——综述
Int J Med Sci. 2020 Oct 18;17(18):2964-2973. doi: 10.7150/ijms.49801. eCollection 2020.
2
Polymeric micelles for anticancer drug delivery.用于抗癌药物递送的聚合物胶束。
Ther Deliv. 2020 Oct;11(10):613-635. doi: 10.4155/tde-2020-0008. Epub 2020 Sep 15.
3
Nanotoxicity: a challenge for future medicine.纳米毒性:未来医学的挑战。
创新实验室技术正在塑造发展中国家的癌症诊断与治疗。
Discov Oncol. 2025 Feb 8;16(1):137. doi: 10.1007/s12672-025-01877-w.
4
Nanotechnology and nanobots unleashed: pioneering a new era in gynecological cancer management - a comprehensive review.纳米技术与纳米机器人的应用:开创妇科癌症管理的新时代——全面综述
Cancer Chemother Pharmacol. 2025 Jan 4;95(1):18. doi: 10.1007/s00280-024-04747-4.
5
What is the Reason That the Pharmacological Future of Chemotherapeutics in the Treatment of Lung Cancer Could Be Most Closely Related to Nanostructures? Platinum Drugs in Therapy of Non-Small and Small Cell Lung Cancer and Their Unexpected, Possible Interactions. The Review.为什么化疗药物在肺癌治疗中的药理前景可能与纳米结构最密切相关?铂类药物在非小细胞肺癌和小细胞肺癌治疗中的作用及其意想不到的可能相互作用。综述。
Int J Nanomedicine. 2024 Sep 14;19:9503-9547. doi: 10.2147/IJN.S469217. eCollection 2024.
6
Nanotechnology Advances in the Detection and Treatment of Lymphoid Malignancies.纳米技术在淋巴恶性肿瘤的检测和治疗中的进展。
Int J Mol Sci. 2024 Aug 26;25(17):9253. doi: 10.3390/ijms25179253.
7
Rheological and Injectability Evaluation of Sterilized Poloxamer-407-Based Hydrogels Containing Docetaxel-Loaded Lipid Nanoparticles.含载多西他赛脂质纳米粒的灭菌泊洛沙姆-407基水凝胶的流变学和可注射性评价
Gels. 2024 May 1;10(5):307. doi: 10.3390/gels10050307.
8
Unleashing the promise of emerging nanomaterials as a sustainable platform to mitigate antimicrobial resistance.释放新兴纳米材料作为减轻抗菌药物耐药性的可持续平台的潜力。
RSC Adv. 2024 May 1;14(20):13862-13899. doi: 10.1039/d3ra05816f. eCollection 2024 Apr 25.
9
Harnessing nature's potential: Alpinia galanga methanolic extract mediated green synthesis of silver nanoparticle, characterization and evaluation of anti-neoplastic activity.利用自然的潜力:益智甲醇提取物介导的银纳米粒子的绿色合成、表征和抗肿瘤活性评价。
Bioprocess Biosyst Eng. 2024 Aug;47(8):1183-1196. doi: 10.1007/s00449-024-02993-7. Epub 2024 Mar 21.
10
The role of nanoparticles and nanomaterials in cancer diagnosis and treatment: a comprehensive review.纳米颗粒和纳米材料在癌症诊断与治疗中的作用:全面综述
Am J Cancer Res. 2023 Dec 15;13(12):5751-5784. eCollection 2023.
Turk J Med Sci. 2020 Jun 23;50(4):1180-1196. doi: 10.3906/sag-1912-209.
4
Gene Therapy in Cancer Treatment: Why Go Nano?癌症治疗中的基因疗法:为何走向纳米?
Pharmaceutics. 2020 Mar 5;12(3):233. doi: 10.3390/pharmaceutics12030233.
5
Current trends and challenges in cancer management and therapy using designer nanomaterials.使用定制纳米材料进行癌症管理与治疗的当前趋势及挑战
Nano Converg. 2019 Jul 15;6(1):23. doi: 10.1186/s40580-019-0193-2.
6
Nano based drug delivery systems: recent developments and future prospects.基于纳米的药物传递系统:最新进展与未来展望。
J Nanobiotechnology. 2018 Sep 19;16(1):71. doi: 10.1186/s12951-018-0392-8.
7
Tumor targeting via EPR: Strategies to enhance patient responses.通过 EPR 进行肿瘤靶向:增强患者反应的策略。
Adv Drug Deliv Rev. 2018 May;130:17-38. doi: 10.1016/j.addr.2018.07.007. Epub 2018 Jul 19.
8
Clinical and biological significance of circulating tumor cells, circulating tumor DNA, and exosomes as biomarkers in colorectal cancer.循环肿瘤细胞、循环肿瘤DNA和外泌体作为生物标志物在结直肠癌中的临床及生物学意义
Oncotarget. 2017 Apr 18;8(33):55632-55645. doi: 10.18632/oncotarget.17184. eCollection 2017 Aug 15.
9
Theranostic Liposome-Nanoparticle Hybrids for Drug Delivery and Bioimaging.用于药物递送和生物成像的诊疗一体化脂质体-纳米颗粒杂化物
Int J Mol Sci. 2017 Jul 2;18(7):1415. doi: 10.3390/ijms18071415.
10
Promising Targets in Anti-cancer Drug Development: Recent Updates.抗癌药物研发中的潜在靶点:最新进展
Curr Med Chem. 2017;24(42):4729-4752. doi: 10.2174/0929867324666170331123648.