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烧伤创面早期加深防治的研究进展

Research advances in prevention and treatment of burn wound deepening in early stage.

作者信息

Lu Meiqi, Zhao Jie, Wang Xiaochuan, Zhang Jingjuan, Shan Fei, Jiang Duyin

机构信息

Department of Burns and Plastic Surgery, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.

Department of Emergency Medical Center, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.

出版信息

Front Surg. 2022 Oct 21;9:1015411. doi: 10.3389/fsurg.2022.1015411. eCollection 2022.

DOI:10.3389/fsurg.2022.1015411
PMID:36338639
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9634408/
Abstract

The burn wound is a dynamic living environment that is affected by many factors. It may present a progressive expansion of necrosis into the initially viable zone of stasis within a short time postburn. Therefore, how to salvage of the zone of stasis is of crucial importance in prevention and treatment strategies of burn wound progressive deepening. This review focuses on the cellular basis of tissue injury and the current progress of prevention and treatment strategies of burn wound progressive deepening, in order to provide references for the treatment of burn wounds in the early phase.

摘要

烧伤创面是一个受多种因素影响的动态生存环境。烧伤后短时间内,它可能会出现坏死向最初的存活停滞区进行性扩展。因此,如何挽救停滞区在烧伤创面进行性加深的防治策略中至关重要。本综述聚焦于组织损伤的细胞基础以及烧伤创面进行性加深防治策略的当前进展,以期为烧伤创面的早期治疗提供参考。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4359/9634408/a719c1d17b33/fsurg-09-1015411-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4359/9634408/a719c1d17b33/fsurg-09-1015411-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4359/9634408/a719c1d17b33/fsurg-09-1015411-g001.jpg

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本文引用的文献

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Int J Biol Macromol. 2022 Sep 1;216:686-697. doi: 10.1016/j.ijbiomac.2022.07.019. Epub 2022 Jul 8.
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Advances of Engineered Hydrogel Organoids within the Stem Cell Field: A Systematic Review.干细胞领域中工程化水凝胶类器官的研究进展:一项系统综述
Gels. 2022 Jun 15;8(6):379. doi: 10.3390/gels8060379.
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Cellular and biological factors involved in healing wounds and burns and treatment options in tissue engineering.
Eur Burn J. 2025 Feb 13;6(1):7. doi: 10.3390/ebj6010007.
4
A scATAC-seq atlas of stasis zone in rat skin burn injury wound process.大鼠皮肤烧伤创面愈合停滞期的单细胞染色质转座酶可及性测序图谱
Front Cell Dev Biol. 2025 Jan 7;12:1519926. doi: 10.3389/fcell.2024.1519926. eCollection 2024.
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Decoding burn trauma: biomarkers for early diagnosis of burn-induced pathologies.解读烧伤创伤:烧伤所致病症早期诊断的生物标志物
Biomark Res. 2024 Dec 23;12(1):160. doi: 10.1186/s40364-024-00707-5.
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Acceleration of wound healing using adipose mesenchymal stem cell secretome hydrogel on partial-thickness cutaneous thermal burn wounds: An study in rats.使用脂肪间充质干细胞分泌组水凝胶促进部分厚度皮肤热烧伤创面愈合:一项大鼠研究。
Vet World. 2024 Jul;17(7):1545-1554. doi: 10.14202/vetworld.2024.1545-1554. Epub 2024 Jul 21.
涉及伤口和烧伤愈合以及组织工程治疗选择的细胞和生物学因素。
Regen Med. 2022 Jun;17(6):401-418. doi: 10.2217/rme-2022-0029. Epub 2022 May 12.
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Progress in Hydrogels for Skin Wound Repair.水凝胶在皮肤创伤修复中的研究进展。
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