1973年至1975年期间，在印度尼西亚泗水进行的霍乱疫苗（普通型和氢氧化铝吸附型）对照现场试验。
A controlled field trial of plain and aluminium hydroxide-adsorbed cholera vaccines in Surabaya, Indonesia, during 1973--75.
作者信息
Saroso J S, Bahrawi W, Witjaksono H, Budiarso R L, Bencić Z, Dewitt W E, Gomez C Z
出版信息
Bull World Health Organ. 1978;56(4):619-27.
A controlled field trial comparing the effectiveness of a plain cholera vaccine with that of a vaccine adsorbed to aluminium hydroxide was carried out in a cholera-endemic area of Indonesia during 1973-75. Tetanus toxoid adsorbed to aluminium phosphate was used as the control. In vaccinees aged 1-4 years, the adsorbed cholera vaccine provided about 88% protection for 6 months following vaccination and still provided about 50% protection between 11 and 14 months after vaccination. In the same age group, the plain vaccine provided only 53% protection during the first 6 months and no appreciable protection beyond that period. In those aged 5 years and over, both vaccines provided 50-60% protection throughout the period of observation (14 months). Neither vaccine caused any serious side effects.
1973年至1975年期间，在印度尼西亚霍乱流行地区进行了一项对照现场试验，比较了普通霍乱疫苗与吸附于氢氧化铝的疫苗的有效性。吸附于磷酸铝的破伤风类毒素用作对照。在1至4岁的疫苗接种者中，吸附霍乱疫苗在接种后6个月提供约88%的保护，在接种后11至14个月仍提供约50%的保护。在同一年龄组中，普通疫苗在前6个月仅提供53%的保护，在此之后没有明显的保护作用。在5岁及以上的人群中，两种疫苗在整个观察期（14个月）内均提供50%-60%的保护。两种疫苗均未引起任何严重的副作用。
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