Li Wanlu, Wang Mian, Ma Huiling, Chapa-Villarreal Fabiola A, Lobo Anderson Oliveira, Zhang Yu Shrike
Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA 02139, USA.
Interdisciplinary Laboratory for Advanced Materials (LIMAV), Materials Science and Engineering Graduate Program (PPGCM), Federal University of Piauí (UFPI), Teresina, PI 64049-550, Brazil.
iScience. 2023 Jan 24;26(2):106039. doi: 10.1016/j.isci.2023.106039. eCollection 2023 Feb 17.
Three-dimensional (3D) bioprinting has emerged as a class of promising techniques in biomedical research for a wide range of related applications. Specifically, stereolithography apparatus (SLA) and digital light processing (DLP)-based vat-polymerization techniques are highly effective methods of bioprinting, which can be used to produce high-resolution and architecturally sophisticated structures. Our review aims to provide an overview of SLA- and DLP-based 3D bioprinting strategies, starting from factors that affect these bioprinting processes. In addition, we summarize the advances in bioinks used in SLA and DLP, including naturally derived and synthetic bioinks. Finally, the biomedical applications of both SLA- and DLP-based bioprinting are discussed, primarily centered on regenerative medicine and tissue modeling engineering.
三维（3D）生物打印已成为生物医学研究中一类具有广阔应用前景的技术，可用于广泛的相关应用。具体而言，基于立体光刻设备（SLA）和数字光处理（DLP）的光固化技术是非常有效的生物打印方法，可用于制造高分辨率和结构复杂的结构。我们的综述旨在从影响这些生物打印过程的因素入手，概述基于SLA和DLP的3D生物打印策略。此外，我们总结了SLA和DLP中使用的生物墨水的进展，包括天然衍生和合成生物墨水。最后，讨论了基于SLA和DLP的生物打印在生物医学方面的应用，主要集中在再生医学和组织建模工程领域。
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