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叶的直接分析及与绿色化学合成 Ag-NPs 和粗水提物相比的连续叶乙醇和水提物的抗微生物活性对一些病原体的作用。

Proximate Analysis of Leaves and the Antimicrobial Activities of Successive Leaf Ethanolic and Aqueous Extracts Compared with Green Chemically Synthesized Ag-NPs and Crude Aqueous Extract against Some Pathogens.

机构信息

Festetics Doctoral School, Institute of Agronomy, Georgikon Campus, Hungarian University of Agriculture and Life Sciences, 8360 Keszthely, Hungary.

Department of Agricultural Biochemistry, Faculty of Agriculture, Cairo University, Giza 12613, Egypt.

出版信息

Int J Mol Sci. 2023 Feb 9;24(4):3529. doi: 10.3390/ijms24043529.

DOI:10.3390/ijms24043529
PMID:36834941
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9960608/
Abstract

Research on the use of different parts of the plant as a nutritional and pharmaceutical resource for human and animals has increased in recent years. This study aimed to investigate the chemical composition and the TPCs and TFCs of Moringa leaves, the antimicrobial activities of Moringa successive ethanolic, aqueous, crude aqueous extracts, and green-chemically synthesized characterized Ag-NPs. The results indicated that the ethanolic extract recorded the highest activity against . On the other side, the aqueous extract showed higher activity, and its effects ranged from 0.03 to 0.33 mg/mL against different strains. The MIC values of Moringa Ag-NPs against different pathogenic bacteria ranged from 0.05 mg/mL to 0.13 mg/mL, and the activity of the crude aqueous extract ranged from 0.15 to 0.83 mg/mL. For the antifungal activity, the ethanolic extract recorded the highest activity at 0.04 mg/mL, and the lowest activity was recorded at 0.42 mg/mL. However, the aqueous extract showed effects ranging from 0.42 to 1.17 mg/mL. Moringa Ag-NPs showed higher activity against the different fungal strains than the crude aqueous extract, and they ranged from 0.25 to 0.83 mg/mL. The MIC values of the Moringa crude aqueous extract ranged from 0.74 to 3.33 mg/mL. Moringa Ag-NPs and their crude aqueous extract may be utilized to boost antimicrobial attributes.

摘要

近年来,人们对将该植物的不同部分作为人类和动物的营养和药用资源的研究有所增加。本研究旨在研究辣木叶的化学成分以及总酚含量和总黄酮含量,以及辣木连续乙醇、水、粗水提物和绿色化学合成的特征 Ag-NPs 的抗菌活性。结果表明,乙醇提取物对 的活性最高。另一方面,水提物表现出更高的活性,其对不同菌株的作用范围为 0.03 至 0.33mg/mL。辣木 Ag-NPs 对不同病原菌的 MIC 值范围为 0.05 至 0.13mg/mL,粗水提物的活性范围为 0.15 至 0.83mg/mL。对于抗真菌活性,乙醇提取物在 0.04mg/mL 时记录到最高活性,而在 0.42mg/mL 时记录到最低活性。然而,水提物表现出 0.42 至 1.17mg/mL 的作用。辣木 Ag-NPs 对不同真菌菌株的活性高于粗水提物,范围为 0.25 至 0.83mg/mL。辣木粗水提物的 MIC 值范围为 0.74 至 3.33mg/mL。辣木 Ag-NPs 及其粗水提物可用于增强抗菌特性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/beb0/9960608/71ae523d8342/ijms-24-03529-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/beb0/9960608/af50bf4de573/ijms-24-03529-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/beb0/9960608/4ba792bbde63/ijms-24-03529-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/beb0/9960608/5192260413bd/ijms-24-03529-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/beb0/9960608/71ae523d8342/ijms-24-03529-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/beb0/9960608/af50bf4de573/ijms-24-03529-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/beb0/9960608/4ba792bbde63/ijms-24-03529-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/beb0/9960608/5192260413bd/ijms-24-03529-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/beb0/9960608/71ae523d8342/ijms-24-03529-g004.jpg

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