Al-Kayali Rawaa S, Kashkash Mohamad F, Alhussein Alhajji Azzam H, Khouri Abdullah
Faculty of Pharmacy, Al-Wataniya Private University, Hama.
Departments of Internal Medicine.
Ann Med Surg (Lond). 2023 Feb 1;85(2):280-283. doi: 10.1097/MS9.0000000000000188. eCollection 2023 Feb.
Currently, coronavirus disease 2019 (COVID-19) and tuberculosis (TB) are among the most important causes of respiratory infections around the world. Both of them are sources of concern for human health and life safety. COVID-19 caused the deaths of millions of people, and many of them suffered from what has become known as 'post-COVID squeal'. Immunosuppression is one of the most important of these symptoms that leave patients susceptible to severe infections like TB.
In these two cases, the authors observed the development of active TB after a period of COVID recovery. Two patients who were admitted to the hospital complained mainly, among other symptoms, of fever and a continuous cough after a period of COVID-19 recovery.
Radiological examination revealed a caving density in the two cases, and the Gene-Xpert test proved the presence of bacteria despite the negative result of the Ziehl-Neelsen stain. The two patients were improved after standard TB treatment.
Patients with post-COVID-19 chronic respiratory symptoms should be screened for TB, especially in TB-endemic areas, even though the result of the Ziehl-Neelsen stain was negative.
目前，2019冠状病毒病（COVID-19）和结核病（TB）是全球最重要的呼吸道感染病因之一。它们都是人类健康和生命安全的关注点。COVID-19导致数百万人死亡，其中许多人患有后来被称为“新冠后遗症”的疾病。免疫抑制是这些症状中最重要的症状之一，使患者易患如结核病等严重感染。
在这两例病例中，作者观察到在COVID恢复一段时间后出现了活动性结核病。两名入院患者在COVID-19恢复一段时间后，除其他症状外，主要抱怨发热和持续咳嗽。
放射学检查显示两例均有密度减低区，尽管萋-尼氏染色结果为阴性，但Gene-Xpert检测证实存在细菌。两名患者经标准抗结核治疗后病情好转。
即使萋-尼氏染色结果为阴性，对于有新冠后慢性呼吸道症状的患者，尤其是在结核病流行地区，也应进行结核病筛查。
