用于工程的合成生物学工具。
Synthetic biology tools for engineering .
作者信息
Kim Gi Yeon, Kim Jinyoung, Park Geunyung, Kim Hyeon Jin, Yang Jina, Seo Sang Woo
机构信息
Interdisciplinary Program in Bioengineering, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, South Korea.
School of Chemical and Biological Engineering, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, South Korea.
出版信息
Comput Struct Biotechnol J. 2023 Mar 6;21:1955-1965. doi: 10.1016/j.csbj.2023.03.004. eCollection 2023.
is a promising organism for the industrial production of amino acids, fuels, and various value-added chemicals. From the whole genome sequence release, has been valuable in the field of industrial microbiology and biotechnology. Continuous discovery of genetic manipulations and regulation mechanisms has developed as a synthetic biology platform chassis. This review summarized diverse genomic manipulation technologies and gene expression tools for static, dynamic, and multiplex control at transcription and translation levels. Moreover, we discussed the current challenges and applicable tools to for future advancements.
是用于氨基酸、燃料和各种增值化学品工业生产的一种很有前景的生物体。从全基因组序列发布以来，在工业微生物学和生物技术领域一直很有价值。遗传操作和调控机制的不断发现已将其发展成为一个合成生物学平台底盘。本综述总结了用于转录和翻译水平的静态、动态和多重控制的多种基因组操作技术和基因表达工具。此外，我们还讨论了当前面临的挑战以及适用于其未来发展的工具。
需注意，原文中部分内容缺失具体指代，翻译可能稍显生硬，但已尽量忠实原文表述。
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