[青少年抑郁症与基因多态性关联的近期研究]
[Recent research on the association between depressive disorder and gene polymorphisms in adolescents].
作者信息
Yao Ke-Ke, Dong Qiang-Li, Ye Lan-Xian
机构信息
Department of Psychiatry, Lanzhou University Second Hospital, Lanzhou 730030, China.
出版信息
Zhongguo Dang Dai Er Ke Za Zhi. 2023 Mar 15;25(3):328-332. doi: 10.7499/j.issn.1008-8830.2208178.
Abstract
Biogenetics plays an important role in the pathogenesis of depressive disorder in adolescents. Various genetic polymorphism studies have updated the understanding of adolescent depressive disorder. However, due to the influence of gene-environment interaction and age of puberty, the influence of gene polymorphisms on adolescent depressive disorder is complicated to clarify. Investigating and clarifying the relationship between gene polymorphisms and adolescent depressive disorder will promote the research on the pathogenesis of this disorder and provide a reference for the prevention and treatment of this disorder. This article reviews the genetic polymorphisms related to adolescent depressive disorder.
摘要
生物遗传学在青少年抑郁症的发病机制中起着重要作用。各种基因多态性研究更新了对青少年抑郁症的认识。然而，由于基因 - 环境相互作用和青春期年龄的影响，基因多态性对青少年抑郁症的影响难以阐明。研究并阐明基因多态性与青少年抑郁症之间的关系将促进对该疾病发病机制的研究，并为该疾病的预防和治疗提供参考。本文综述了与青少年抑郁症相关的基因多态性。
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