Research Center for Environmental Ecology and Engineering, School of Environmental Ecology and Biological Engineering, Wuhan Institute of Technology, Wuhan 430205, China.
Molecules. 2023 Mar 7;28(6):2432. doi: 10.3390/molecules28062432.
Biofilms are microbial aggregation membranes that are formed when microorganisms attach to the surfaces of living or nonliving things. Importantly, biofilm properties provide microorganisms with protection against environmental pressures and enhance their resistance to antimicrobial agents, contributing to microbial persistence and toxicity. Thus, bacterial biofilm formation is part of the bacterial survival mechanism. However, if foodborne pathogens form biofilms, the risk of foodborne disease infections can be greatly exacerbated, which can cause major public health risks and lead to adverse economic consequences. Therefore, research on biofilms and their removal strategies are very important in the food industry. Food waste due to spoilage within the food industry remains a global challenge to environmental sustainability and the security of food supplies. This review describes bacterial biofilm formation, elaborates on the problem associated with biofilms in the food industry, enumerates several kinds of common foodborne pathogens in biofilms, summarizes the current strategies used to eliminate or control harmful bacterial biofilm formation, introduces the current and emerging control strategies, and emphasizes future development prospects with respect to bacterial biofilms.
生物膜是微生物附着在生物或非生物表面时形成的微生物聚集膜。重要的是，生物膜特性为微生物提供了对环境压力的保护，并增强了它们对抗菌剂的抵抗力，从而促进了微生物的持久性和毒性。因此，细菌生物膜的形成是细菌生存机制的一部分。然而，如果食源性病原体形成生物膜，食源性疾病感染的风险可能会大大加剧，这可能会带来重大的公共卫生风险，并导致不良的经济后果。因此，研究生物膜及其去除策略在食品工业中非常重要。食品工业中由于食品变质而导致的食物浪费仍然是对环境可持续性和食品安全供应的全球性挑战。本文描述了细菌生物膜的形成，阐述了生物膜在食品工业中存在的问题，列举了几种常见的食源性病原体在生物膜中的存在，总结了目前用于消除或控制有害细菌生物膜形成的策略，介绍了目前和新兴的控制策略，并强调了细菌生物膜未来的发展前景。
