Bhattacharya Tanima, Shin Gye Hwa, Kim Jun Tae
Department of Food and Nutrition, Kyung Hee University, Seoul 02447, Republic of Korea.
Department of Food and Nutrition, Kunsan National University, Gunsan 54150, Republic of Korea.
Pharmaceutics. 2023 Mar 22;15(3):1019. doi: 10.3390/pharmaceutics15031019.
Recently, carbon dots (CDs) have been actively studied and reported for their various properties. In particular, the specific characteristics of carbon dots have been considered as a possible technique for cancer diagnosis and therapy. This is also a cutting-edge technology that offers fresh ideas for treating various disorders. Though carbon dots are still in their infancy and have not yet shown their value to society, their discovery has already resulted in some noteworthy advancements. The application of CDs indicates conversion in natural imaging. Photography using CDs has demonstrated extraordinary appropriateness in bio-imaging, the discovery of novel drugs, the delivery of targeted genes, bio-sensing, photodynamic therapy, and diagnosis. This review seeks to provide a comprehensive understanding of CDs, including their benefits, characteristics, applications, and mode of action. In this overview, many CD design strategies will be highlighted. In addition, we will discuss numerous studies on cytotoxic testing to demonstrate the safety of CDs. The current study will address the production method, mechanism, ongoing research, and application of CDs in cancer diagnosis and therapy.
近年来，碳点（CDs）因其各种特性而受到积极研究和报道。特别是，碳点的特定特性被视为一种可能用于癌症诊断和治疗的技术。这也是一项前沿技术，为治疗各种疾病提供了新的思路。尽管碳点仍处于起步阶段，尚未向社会展现其价值，但其发现已带来了一些值得注意的进展。碳点的应用表明了在自然成像方面的转变。使用碳点的摄影在生物成像、新药发现、靶向基因递送、生物传感、光动力疗法和诊断中已显示出非凡的适用性。本综述旨在全面介绍碳点，包括其优点、特性、应用和作用方式。在本概述中，将重点介绍许多碳点设计策略。此外，我们将讨论大量关于细胞毒性测试的研究，以证明碳点的安全性。当前的研究将阐述碳点在癌症诊断和治疗中的生产方法、作用机制、正在进行的研究以及应用。
