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在《新型体重增加预防研究(SNAP)试验》中,预防体重增加的干预措施促进了年轻人的理想心血管健康。

Weight gain prevention interventions in the Study of Novel Approaches to Weight Gain Prevention (SNAP) trial promote ideal cardiovascular health in young adults.

机构信息

Weight Control and Diabetes Research Center, The Miriam Hospital and Department of Psychiatry and Human Behavior, Warren Alpert Medical School, Brown University, Providence, Rhode Island, USA.

Department of Health Behavior and Policy, Virginia Commonwealth University School of Medicine, Richmond, Virginia, USA.

出版信息

Obesity (Silver Spring). 2023 Jun;31(6):1530-1537. doi: 10.1002/oby.23753. Epub 2023 May 8.

Abstract

OBJECTIVE

Cardiovascular health (CVH) declines in young adulthood. This study assessed whether weight gain prevention interventions promoted ideal CVH.

METHODS

Young adults (n = 599; age 18-35 years; BMI: 21.0-30.9 kg/m ) from a randomized controlled trial comparing two weight gain prevention interventions (self-regulation with large or small changes) and a self-guided control group completed anthropometric and clinical assessments at baseline and 2 years. CVH was quantified via the American Heart Association's Life's Simple 7 (LS7) number of ideal components met.

RESULTS

Both interventions showed significant improvements in the average number of ideal LS7 components met at 2 years compared with control (pre- to post-treatment means; large change: 0.24, small change: 0.34, control: -0.2, p < 0.05). Moreover, a greater percentage of participants in both interventions improved by ≥1 ideal component (large change: 35%, small change: 37%, control: 29%) and a smaller percentage declined by ≥1 ideal component (large change: 16%, small change: 20%, control: 30%) compared with control. For individual LS7 components, the odds of having an ideal BMI and glucose varied by treatment condition at 2 years.

CONCLUSIONS

Two weight gain prevention interventions led to improvements in ideal CVH at 2 years. Interventions explicitly focused on a broader constellation of LS7 domains might lead to even greater changes in CVH.

摘要

目的

心血管健康(CVH)在青年期下降。本研究评估了体重增加预防干预是否促进了理想的 CVH。

方法

来自一项比较两种体重增加预防干预措施(自我调节大或小变化)和自我指导对照组的随机对照试验的年轻成年人(n=599;年龄 18-35 岁;BMI:21.0-30.9kg/m)在基线和 2 年时完成了人体测量和临床评估。CVH 通过美国心脏协会的生命简单 7(LS7)达到理想成分的数量来量化。

结果

与对照组相比,两种干预措施在 2 年内平均达到理想 LS7 成分的数量都有显著改善(治疗前至治疗后均值;大变化:0.24,小变化:0.34,对照组:-0.2,p<0.05)。此外,两种干预措施中都有更多的参与者改善了≥1 个理想成分(大变化:35%,小变化:37%,对照组:29%),而下降≥1 个理想成分的参与者比例较小(大变化:16%,小变化:20%,对照组:30%)。对于个别 LS7 成分,在 2 年内,理想 BMI 和葡萄糖的可能性因治疗条件而异。

结论

两种体重增加预防干预措施在 2 年内导致了理想 CVH 的改善。专门针对 LS7 领域更广泛组合的干预措施可能会导致 CVH 更大的变化。

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