Papanin Institute for Biology of Inland Waters, Russian Academy of Sciences, Borok 152742, Russia.
Int J Mol Sci. 2023 Jul 1;24(13):10989. doi: 10.3390/ijms241310989.
This review covers the phenomenon of resonance-like responses of biological systems to low-frequency magnetic fields (LFMF). The historical development of this branch of magnetobiology, including the most notable biophysical models that explain the resonance-like responses of biological systems to LFMF with a specific frequency and amplitude, is given. Two groups can be distinguished among these models: one considers ion-cofactors of proteins as the primary targets for the LFMF influence, and the other regards the magnetic moments of particles in biomolecules. Attention is paid to the dependence of resonance-like LFMF effects on the cell type. A radical-pair mechanism of the magnetic field's influence on biochemical processes is described with the example of cryptochrome. Conditions for this mechanism's applicability to explain the biological effects of LFMF are given. A model of the influence of LFMF on radical pairs in biochemical oscillators, which can explain the frequency-amplitude efficiency windows of LFMF, is proposed.
本文综述了生物系统对低频磁场（LFMF）产生共振样响应的现象。给出了该磁生物学分支的历史发展，包括用特定频率和幅度解释生物系统对 LFMF 产生共振样响应的最显著的生物物理模型。这些模型可以分为两类：一类认为蛋白质的离子辅助因子是 LFMF 影响的主要靶点，另一类则认为是生物分子中颗粒的磁矩。文中还关注了共振样 LFMF 效应与细胞类型的依赖性。本文以隐花色素为例，描述了磁场对生化过程影响的自由基对机制。给出了该机制适用于解释 LFMF 生物效应的条件。还提出了一种 LFMF 对生化振荡器中自由基对影响的模型，该模型可以解释 LFMF 的频率-幅度效率窗口。
