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基于深度互学习的乳腺癌组织病理学图像诊断

Histopathological Image Diagnosis for Breast Cancer Diagnosis Based on Deep Mutual Learning.

作者信息

Kaur Amandeep, Kaushal Chetna, Sandhu Jasjeet Kaur, Damaševičius Robertas, Thakur Neetika

机构信息

Chitkara University Institute of Engineering and Technology, Chitkara University, Rajpura 140401, India.

Department of Applied Informatics, Vytautas Magnus University, 53361 Akademija, Lithuania.

出版信息

Diagnostics (Basel). 2023 Dec 31;14(1):95. doi: 10.3390/diagnostics14010095.

Abstract

Every year, millions of women across the globe are diagnosed with breast cancer (BC), an illness that is both common and potentially fatal. To provide effective therapy and enhance patient outcomes, it is essential to make an accurate diagnosis as soon as possible. In recent years, deep-learning (DL) approaches have shown great effectiveness in a variety of medical imaging applications, including the processing of histopathological images. Using DL techniques, the objective of this study is to recover the detection of BC by merging qualitative and quantitative data. Using deep mutual learning (DML), the emphasis of this research was on BC. In addition, a wide variety of breast cancer imaging modalities were investigated to assess the distinction between aggressive and benign BC. Based on this, deep convolutional neural networks (DCNNs) have been established to assess histopathological images of BC. In terms of the Break His-200×, BACH, and PUIH datasets, the results of the trials indicate that the level of accuracy achieved by the DML model is 98.97%, 96.78, and 96.34, respectively. This indicates that the DML model outperforms and has the greatest value among the other methodologies. To be more specific, it improves the results of localization without compromising the performance of the classification, which is an indication of its increased utility. We intend to proceed with the development of the diagnostic model to make it more applicable to clinical settings.

摘要

每年,全球数百万女性被诊断出患有乳腺癌(BC),这种疾病既常见又可能致命。为了提供有效的治疗并改善患者预后,尽快做出准确诊断至关重要。近年来,深度学习(DL)方法在包括组织病理学图像处理在内的各种医学成像应用中显示出巨大成效。利用DL技术,本研究的目的是通过合并定性和定量数据来恢复对BC的检测。使用深度互学习(DML),本研究重点关注BC。此外,还研究了多种乳腺癌成像模式,以评估侵袭性和良性BC之间的区别。基于此,已建立深度卷积神经网络(DCNN)来评估BC的组织病理学图像。就Break His - 200×、BACH和PUIH数据集而言,试验结果表明DML模型实现的准确率分别为98.97%、96.78和96.34。这表明DML模型在其他方法中表现更优且具有最大价值。更具体地说,它在不影响分类性能的情况下提高了定位结果,这表明其效用有所增加。我们打算继续开发诊断模型,使其更适用于临床环境。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6983/10795733/ea0c012c63c3/diagnostics-14-00095-g001.jpg

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