Medical Sciences, Islamic Azad University, Mashhad, Iran.
Department of Community Medicine, Islamic Azad University, Mashhad, Iran.
BMJ Open Gastroenterol. 2024 Apr 4;11(1):e001298. doi: 10.1136/bmjgast-2023-001298.
The Gastroesophageal Reflux Disease Health-Related Quality of Life (GERD-HRQL) is one of the most widely used questionnaires for assessing typical gastro-oesophageal reflux disease (GORD) symptoms. It is simple, concise, and treatment responsive, yet it has not been validated in the Persian language. This study aimed to translate the GERD-HRQL questionnaire into Persian and assess its validity and reliability.
In this cross-sectional validation study, a team of gastroenterologists, general surgeons, and professional translators conducted the forward-backward translation. A gastroenterologist interviewed 10 patients with GORD to insure understandability of the questionnaire. Fifty-four patients with GORD and 60 patients with gastrointestinal complaints other than GORD were enrolled using convenience sampling method. To assess concurrent validity, patients with GORD completed the Persian GERD-HRQL and the WHO Quality of Life Brief Version (WHOQOL-BREF) questionnaires. To assess discriminant validity, GERD-HRQL scores were compared between GORD and non-GORD patients. After 2 weeks, the patients with GORD completed the GERD-HRQL questionnaire again to assess test-retest reliability. The internal consistency was measured using Cronbach's alpha.
The mean age of the GORD participants was 36.90±10.44, and the majority were women (78%). All GERD-HRQL domains and total scores exhibited significant negative correlations with WHOQOL-BREF domains (ranging from -0.28 to -0.97). The GERD-HRQL scores were significantly different in GORD and non-GORD patients (p<0.001). Test and retest scores did not show any significant differences (p=0.49). Cronbach's alpha was 0.85.
The Persian GERD-HRQL questionnaire is valid and reliable and can effectively assess the GORD symptoms in Persian-speaking individuals.
胃食管反流病健康相关生活质量（GERD-HRQL）问卷是评估典型胃食管反流病（GORD）症状最广泛使用的问卷之一。它简单、简洁且对治疗有反应，但尚未在波斯语中得到验证。本研究旨在将 GERD-HRQL 问卷翻译成波斯语，并评估其有效性和可靠性。
在这项横断面验证研究中，一组胃肠病学家、普通外科医生和专业翻译人员进行了正向-反向翻译。一位胃肠病学家对 10 名 GORD 患者进行了访谈，以确保问卷的可理解性。使用便利抽样法招募了 54 名 GORD 患者和 60 名胃肠道疾病（非 GORD）患者。为了评估同时效性，GORD 患者完成了波斯语 GERD-HRQL 和世界卫生组织生活质量简明量表（WHOQOL-BREF）问卷。为了评估判别有效性，比较了 GORD 和非 GORD 患者的 GERD-HRQL 评分。2 周后，GORD 患者再次完成 GERD-HRQL 问卷以评估测试-重测信度。使用 Cronbach's alpha 测量内部一致性。
GORD 参与者的平均年龄为 36.90±10.44 岁，大多数为女性（78%）。所有 GERD-HRQL 领域和总分与 WHOQOL-BREF 领域均呈显著负相关（范围从-0.28 到-0.97）。GORD 和非 GORD 患者的 GERD-HRQL 评分差异显著（p<0.001）。测试和重测评分没有显著差异（p=0.49）。Cronbach's alpha 为 0.85。
波斯语 GERD-HRQL 问卷具有有效性和可靠性，能够有效评估波斯语个体的 GORD 症状。
