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人工智能在肿瘤学中的应用:现状、挑战与未来方向。

Artificial Intelligence in Oncology: Current Landscape, Challenges, and Future Directions.

机构信息

Department of Data Science, Dana-Farber Cancer Institute, Boston, Massachusetts.

Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts.

出版信息

Cancer Discov. 2024 May 1;14(5):711-726. doi: 10.1158/2159-8290.CD-23-1199.


DOI:10.1158/2159-8290.CD-23-1199
PMID:38597966
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11131133/
Abstract

UNLABELLED: Artificial intelligence (AI) in oncology is advancing beyond algorithm development to integration into clinical practice. This review describes the current state of the field, with a specific focus on clinical integration. AI applications are structured according to cancer type and clinical domain, focusing on the four most common cancers and tasks of detection, diagnosis, and treatment. These applications encompass various data modalities, including imaging, genomics, and medical records. We conclude with a summary of existing challenges, evolving solutions, and potential future directions for the field. SIGNIFICANCE: AI is increasingly being applied to all aspects of oncology, where several applications are maturing beyond research and development to direct clinical integration. This review summarizes the current state of the field through the lens of clinical translation along the clinical care continuum. Emerging areas are also highlighted, along with common challenges, evolving solutions, and potential future directions for the field.

摘要

未加标签:肿瘤学中的人工智能(AI)正在超越算法开发,融入临床实践。本综述描述了该领域的现状,特别关注临床整合。根据癌症类型和临床领域对 AI 应用进行了结构化分类,重点关注最常见的四种癌症和检测、诊断和治疗这四项任务。这些应用涵盖了各种数据模式,包括成像、基因组学和医疗记录。最后,我们总结了该领域目前存在的挑战、不断发展的解决方案以及潜在的未来方向。

意义:人工智能正越来越多地应用于肿瘤学的各个方面,其中一些应用正在从研发阶段走向成熟,直接进入临床整合。本综述通过沿着临床护理连续体的视角,对该领域的现状进行了总结。还突出了新兴领域,以及该领域目前存在的挑战、不断发展的解决方案和潜在的未来方向。

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[1]
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JAMA Pediatr. 2025-2-1

[2]
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Nat Mach Intell. 2023-7

[3]
SPeC: A Soft Prompt-Based Calibration on Performance Variability of Large Language Model in Clinical Notes Summarization.

J Biomed Inform. 2024-3

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NEJM Evid. 2023-8

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Nat Med. 2024-1

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[9]
Accurate proteome-wide missense variant effect prediction with AlphaMissense.

Science. 2023-9-22

[10]
Role of Artificial Intelligence in Colonoscopy Detection of Advanced Neoplasias : A Randomized Trial.

Ann Intern Med. 2023-9

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