Shi Huaiyu, Kowalczewski Andrew, Vu Danny, Liu Xiyuan, Salekin Asif, Yang Huaxiao, Ma Zhen
Department of Biomedical & Chemical Engineering, Syracuse University, Syracuse, NY, USA.
BioInspired Institute for Material and Living Systems, Syracuse University, Syracuse, NY, USA.
Med Nov Technol Devices. 2024 Mar;21. doi: 10.1016/j.medntd.2023.100276. Epub 2023 Nov 27.
Organoid Intelligence ushers in a new era by seamlessly integrating cutting-edge organoid technology with the power of artificial intelligence. Organoids, three-dimensional miniature organ-like structures cultivated from stem cells, offer an unparalleled opportunity to simulate complex human organ systems in vitro. Through the convergence of organoid technology and AI, researchers gain the means to accelerate discoveries and insights across various disciplines. Artificial intelligence algorithms enable the comprehensive analysis of intricate organoid behaviors, intricate cellular interactions, and dynamic responses to stimuli. This synergy empowers the development of predictive models, precise disease simulations, and personalized medicine approaches, revolutionizing our understanding of human development, disease mechanisms, and therapeutic interventions. Organoid Intelligence holds the promise of reshaping how we perceive in vitro modeling, propelling us toward a future where these advanced systems play a pivotal role in biomedical research and drug development.
类器官智能通过将前沿的类器官技术与人工智能的力量无缝整合，开启了一个新时代。类器官是由干细胞培育而成的三维微型器官样结构，为在体外模拟复杂的人体器官系统提供了无与伦比的机会。通过类器官技术与人工智能的融合，研究人员获得了加速各学科发现和见解的手段。人工智能算法能够对复杂的类器官行为、复杂的细胞相互作用以及对刺激的动态反应进行全面分析。这种协同作用推动了预测模型、精确疾病模拟和个性化医疗方法的发展，彻底改变了我们对人类发育、疾病机制和治疗干预的理解。类器官智能有望重塑我们对体外建模的认知，推动我们迈向一个未来，在这个未来中，这些先进系统将在生物医学研究和药物开发中发挥关键作用。
