Department of Community Health Sciences, Aga Khan University, Karachi, Pakistan.
Department of Surgery, Aga Khan University, Karachi, Pakistan.
Sci Rep. 2024 Apr 30;14(1):9951. doi: 10.1038/s41598-024-60659-6.
Due to the overlapping aetiology of Gestational Diabetes Mellitus (GDM) and Periodontal disease (PD), which are prevalent metabolic disorder and chronic inflammatory disorder in pregnant women respectively, they are often at risk of developing both diseases simultaneously. This study aims to evaluate the association of periodontal disease and gestational diabetes mellitus among post-partum women who delivered within 24 h at private tertiary care hospital, Karachi, Pakistan. Analytical cross sectional study with sample size of 178 by non- probability purposive sampling, a total of 101 postpartum women (57%) were diagnosed with periodontal disease and 50 (28%) were GDM positive. Of those who had PD, 35% (n = 35/101) were GDM positive. An insignificant association of the prevalence ratio of GDM in women with periodontal disease was found. [PR = 1.7; 95% CI: 0.2-3.2; p-value 0.07] A statistically significant association was found between the prevalence ratio of GDM in women with obesity. It was 2.6 times compared to women who were not obese (p value < 0.01, 95% CI: 1.3-5.1). There is insignificant association found between the prevalence ratio of GDM in women with periodontal disease in our setting. Women who are overweight or tend to gain weight should be closely monitored and guided to take dietary measures.
由于妊娠糖尿病（GDM）和牙周病（PD）的病因重叠，这两种疾病分别是孕妇中常见的代谢紊乱和慢性炎症性疾病，因此她们通常同时面临这两种疾病的风险。本研究旨在评估巴基斯坦卡拉奇一家私立三级保健医院分娩后 24 小时内的产后妇女中牙周病与妊娠糖尿病之间的关系。这是一项采用非概率目的抽样的分析性横断面研究，样本量为 178 名，其中 101 名（57%）产后妇女被诊断患有牙周病，50 名（28%）患有 GDM。在患有 PD 的患者中，有 35%（n=35/101）患有 GDM。患有牙周病的妇女中 GDM 的患病率比没有牙周病的妇女高，但差异无统计学意义。[PR=1.7；95%CI：0.2-3.2；p 值 0.07]。患有肥胖症的妇女中 GDM 的患病率比没有肥胖症的妇女高，差异有统计学意义。肥胖症妇女的患病率比非肥胖症妇女高 2.6 倍（p 值<0.01，95%CI：1.3-5.1）。在我们的研究中，患有牙周病的妇女中 GDM 的患病率比没有牙周病的妇女高，但差异无统计学意义。超重或有体重增加趋势的妇女应密切监测并指导其采取饮食措施。
