抗Ro（SSA）阳性类风湿关节炎（RA）：一组D-青霉胺副作用发生率高的临床血清学患者。
Anti-Ro(SSA) positive rheumatoid arthritis (RA): a clinicoserological group of patients with high incidence of D-penicillamine side effects.
作者信息
Moutsopoulos H M, Skopouli F N, Sarras A K, Tsampoulas C, Mavridis A K, Constantopoulos S H, Maddison P J
出版信息
Ann Rheum Dis. 1985 Apr;44(4):215-9. doi: 10.1136/ard.44.4.215.
Abstract
The clinical, laboratory, histological, and radiological manifestations of 90 Greek patients with anti-Ro(SSA) negative rheumatoid arthritis (RA) were compared with those of 15 Greek patients with anti-Ro(SSA) positive RA. Anti-Ro(SSA) positive RA patients had the same articular and extra-articular manifestations as anti-Ro(SSA) negative patients. However, they were predominantly females with lower rheumatoid factor titres and a high incidence of positive minor salivary gland biopsy specimens for Sjögren's syndrome. Finally, anti-Ro(SSA) positive RA patients frequently experienced penicillamine side effects.
摘要
将90例抗Ro(SSA)阴性类风湿性关节炎（RA）希腊患者的临床、实验室、组织学和放射学表现与15例抗Ro(SSA)阳性RA希腊患者的表现进行了比较。抗Ro(SSA)阳性RA患者与抗Ro(SSA)阴性患者具有相同的关节和关节外表现。然而，他们主要为女性，类风湿因子滴度较低，小唾液腺活检标本中干燥综合征阳性的发生率较高。最后，抗Ro(SSA)阳性RA患者经常出现青霉胺副作用。
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