Mecha Mohammed, Sisay Yordanos, Melaku Tsegaye
Department of Internal Medicine, Institute of Health, Jimma University, Ethiopia.
Department of Epidemiology, Wolaita Sodo University, Ethiopia.
Int J Cardiol Cardiovasc Risk Prev. 2024 May 17;21:200288. doi: 10.1016/j.ijcrp.2024.200288. eCollection 2024 Jun.
Diabetes mellitus (DM) is a chronic metabolic condition that considerably increases the risk of stroke. According to studies, stroke patients with diabetes have a greater mortality rate and are more likely to have repeated strokes than those without diabetes. Therefore, this systematic review and meta-analysis determined the pooled prevalence of diabetes mellitus among stroke patients in Ethiopia.
The searches were conducted in electronic databases such as PubMed/MEDLINE, EMBASE, Science Direct, Web of Science, and Google Scholar. Observational study designs were selected, and studies published until November 30, 2023, addressing the prevalence of diabetes mellitus among stroke patients were identified. EndNote Citation Manager software version X for Windows was used to collect and organize the search outcomes and remove duplicate articles. Relevant data were extracted from the included studies using a format prepared in Microsoft Excel and exported to STATA 18.0 software for outcome measures analyses and subgrouping.
Twenty-eight research articles were included in the final analysis. The studies included an evaluation of 6589 stroke patients, among whom 645 were diagnosed with DM. This resulted in a pooled prevalence estimate of 10 % (95 % CI: 8-13 %)] DM. The subgroup analysis by region revealed that the highest pooled prevalence of DM was 16 % [95 % CI: (9 %-24 %)], which was from the Oromia region, followed by Addis Ababa city 12 % [95 % CI: (10 %-14 %)]. The other three regions (Tigray, South Nations nationalities and people's region and Amhara) had similar pooled prevalence of DM 7 % [95 % CI: (3 %-10 %)], 7 % [95 % CI: (3 %-11 %)], 7 % [95 % CI: (4 %-9%)], respectively.
Overall, the prevalence of DM among stroke patients is high. Notably, the Oromia region exhibited the highest prevalence rate at 16 %, followed by Addis Ababa city at 12 %. Conversely, the other three regions displayed similar rates of 7 %. These findings underscore the critical importance of screening and managing DM in stroke patients.
糖尿病(DM)是一种慢性代谢性疾病,会显著增加中风风险。根据研究,与非糖尿病患者相比,糖尿病中风患者的死亡率更高,且更易复发中风。因此,本系统评价和荟萃分析确定了埃塞俄比亚中风患者中糖尿病的合并患病率。
在PubMed/MEDLINE、EMBASE、Science Direct、Web of Science和谷歌学术等电子数据库中进行检索。选择观察性研究设计,并识别截至2023年11月30日发表的有关中风患者糖尿病患病率的研究。使用适用于Windows的EndNote Citation Manager软件版本X收集和整理检索结果,并去除重复文章。使用在Microsoft Excel中准备的格式从纳入研究中提取相关数据,并导出到STATA 18.0软件进行结果测量分析和亚组划分。
最终分析纳入了28篇研究文章。这些研究共评估了6589名中风患者,其中645人被诊断为糖尿病。这导致糖尿病的合并患病率估计为10%(95%CI:8%-13%)。按地区进行的亚组分析显示,糖尿病合并患病率最高的是奥罗米亚地区,为16%[95%CI:(9%-24%)],其次是亚的斯亚贝巴市,为12%[95%CI:(10%-14%)]。其他三个地区(提格雷、南方各族州和阿姆哈拉)的糖尿病合并患病率相似,分别为7%[95%CI:(3%-10%)]、7%[95%CI:(3%-11%)]和7%[95%CI:(-4%-9%)]。
总体而言,中风患者中糖尿病的患病率较高。值得注意的是,奥罗米亚地区的患病率最高,为16%,其次是亚的斯亚贝巴市,为12%。相反,其他三个地区的患病率相似,为7%。这些发现强调了对中风患者进行糖尿病筛查和管理的至关重要性。