Cardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Avicenna Fertility Center, Avicenna Research Institute (ARI), ACECR, Tehran, Iran.
Eur J Nutr. 2024 Oct;63(7):2407-2419. doi: 10.1007/s00394-024-03470-3. Epub 2024 Jul 28.
One highlighted pathogenesis mechanism of diseases is the negative impact of pro-inflammatory diets (PD) on the gut microbiome. This systematic review aimed to study the link between dietary inflammatory index (DII), as an indicator of PD, and gut microbiome.
A systematic search was done in PubMed and Scopus, adhering to the guidelines of Preferred Reporting Items for Systematic Reviews and Meta-Analysis. The assessment of the included studies' quality was performed using the critical appraisal checklist from the Joanna Briggs Institute.
Ten articles were included eight cross-sectional, one case-control, and, one cohort study. Seven and three included articles reported a weak and moderate relationship between gut microbiome and DII scores, respectively. DII scores were linked to variety in microbiome composition and diversity/richness. More importantly, anti-inflammatory diets as measured by lower DII scores were linked to a more desirable gut microbiome profile. Prevotella stercorea, Veillonella rogosae, Morganella morganii, Ruminococcus torques, Eubacterium nodatum, Alistipes intestine, Clostridium leptum, Morganellaceae family, Enterobacteriaceae family, and, Bacteroides thetaiotaomicron were related to higher DII scores. While, Butyrate-producing bacteria such as Ruminococcaceae and Lachnospiraceae families, Faecalibacterium prausnitzii, and Akkermansia muciniphila were related to lower DII scores.
An anti-inflammatory diet, as measured by a lower DII score, might be linked to variations in the composition and variety of the microbiome. Therefore, the DII score could be useful in microbiota research, however, this possibility needs to be investigated more precisely in future studies.
疾病的一个突出发病机制是促炎饮食（PD）对肠道微生物组的负面影响。本系统评价旨在研究饮食炎症指数（DII）作为 PD 指标与肠道微生物组之间的联系。
在 PubMed 和 Scopus 中进行了系统搜索，遵循系统评价和荟萃分析的首选报告项目指南。使用 Joanna Briggs 研究所的批判性评估清单评估纳入研究的质量。
纳入了 10 篇文章，其中 8 篇为横断面研究，1 篇为病例对照研究，1 篇为队列研究。有 7 篇和 3 篇文章分别报道了肠道微生物组和 DII 评分之间的弱和中度关系。DII 评分与微生物组组成和多样性/丰富度的变化有关。更重要的是，抗炎饮食（通过较低的 DII 评分来衡量）与更理想的肠道微生物组特征有关。Prevotella stercorea、Veillonella rogosae、Morganella morganii、Ruminococcus torques、Eubacterium nodatum、Alistipes intestine、Clostridium leptum、Morganellaceae 家族、Enterobacteriaceae 家族和 Bacteroides thetaiotaomicron 与较高的 DII 评分有关。而产丁酸细菌，如 Ruminococcaceae 和 Lachnospiraceae 家族、Faecalibacterium prausnitzii 和 Akkermansia muciniphila 与较低的 DII 评分有关。
抗炎饮食（通过较低的 DII 评分来衡量）可能与微生物组的组成和多样性变化有关。因此，DII 评分可能对微生物组研究有用，但是，这一可能性需要在未来的研究中更精确地进行调查。
