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非洲之角未确诊高血压的趋势、负担和决定因素:系统评价和荟萃分析。

Trend, burden and determinants of undiagnosed hypertension in the Horn of Africa: A systematic review and meta-analysis.

机构信息

Department of Epidemiology and Biostatistics, Institute of Public Health, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.

Department of Nursing, College of Health Science, Debark University, Debark, Ethiopia.

出版信息

PLoS One. 2024 Aug 23;19(8):e0303940. doi: 10.1371/journal.pone.0303940. eCollection 2024.

Abstract

BACKGROUND

Hypertension is a silent killer disease and the global report revealed that half of the world's population lives with undiagnosed hypertension. The problem is expected to be worse in low-income countries such as in Horn of Africa countries. Thus, we planned to determine the trend, burden, and determinates of undiagnosed hypertension in this region and provide conclusive and tangible evidence for interventions.

METHOD

Articles were searched on Google, Google Scholar, PubMed/Medline, EMBASE, SCOPUS, and the published articles' reference list. The JBI critical appraisal checklist was used for quality assessment. A sensitivity test and I2 statistics were conducted to evaluate the heterogeneity. The Begg's statistics in the random effect model were done to evaluate the publication bias.

RESULT

The pooled prevalence of undiagnosed hypertension in the Horn of Africa was 17% (95% CI: 15%-20%) and it ranges from from 13% in 2006 to 20% in 2023. A trip time to a medical institution of less than 35 minutes (OR = 0.52, 95%CI: 0.35-0.79), no regular exercise (OR = 2.26, 95% CI: 1.54-3.32), age > = 45 years (OR = 2.51, 95% CI: 1.66-3.8), age 35-44 years (OR = 1.88, 95% CI: 1.5-2.37), male (OR = 1.72, 95% CI: 1.34-2.2), poor knowledge (OR = 3.29, 95%CI: 2.39,4.53), normal BMI (OR = 3.84, 95% CI: 2.96-4.98), Overweight (OR = 1.97, 95% CI: 2.96-4.98), poor health seeking (OR = 2.79, 95%CI: 2.01-3.86), low vegetable consumers (OR = 1.99, 95%CI:1.36-2.91), smoking (OR = 1.47, 95%CI: 1.13-1.93), high triglyceride (OR = 1.83, 95%CI:1.33-2.52), chat chewing (OR = 2.18, 95%CI: 1.54-3.09), and alcohol drinking (OR = 1.75, 95%CI: 1.32-2.33) were the determinats of undiagnosed hypertension.

CONCLUSION AND RECOMMENDATION

The pooled prevalence of undiagnosed hypertension was low in the Horn of Africa but its trend was increased over time. Individual level variables were identified that affect the undiagnosed hypertension. Therefore, healthy lifestyle is recommended.

摘要

背景

高血压是一种无声的杀手疾病,全球报告显示,世界上一半的人口患有未确诊的高血压。预计在非洲之角等低收入国家,这个问题会更加严重。因此,我们计划确定该地区未确诊高血压的趋势、负担和决定因素,并为干预措施提供确凿和切实可行的证据。

方法

在 Google、Google Scholar、PubMed/Medline、EMBASE、SCOPUS 上搜索文章,并查阅已发表文章的参考文献列表。使用 JBI 批判性评估清单评估质量。进行敏感性测试和 I2 统计以评估异质性。使用随机效应模型中的 Begg 统计量评估发表偏倚。

结果

非洲之角未确诊高血压的总患病率为 17%(95%CI:15%-20%),范围从 2006 年的 13%到 2023 年的 20%。到医疗机构的旅行时间少于 35 分钟(OR = 0.52,95%CI:0.35-0.79)、没有定期锻炼(OR = 2.26,95%CI:1.54-3.32)、年龄≥45 岁(OR = 2.51,95%CI:1.66-3.8)、35-44 岁(OR = 1.88,95%CI:1.5-2.37)、男性(OR = 1.72,95%CI:1.34-2.2)、知识水平低(OR = 3.29,95%CI:2.39-4.53)、正常体重指数(OR = 3.84,95%CI:2.96-4.98)、超重(OR = 1.97,95%CI:2.96-4.98)、不良健康寻求(OR = 2.79,95%CI:2.01-3.86)、蔬菜摄入量低(OR = 1.99,95%CI:1.36-2.91)、吸烟(OR = 1.47,95%CI:1.13-1.93)、高甘油三酯(OR = 1.83,95%CI:1.33-2.52)、咀嚼(OR = 2.18,95%CI:1.54-3.09)和饮酒(OR = 1.75,95%CI:1.32-2.33)是未确诊高血压的决定因素。

结论和建议

非洲之角未确诊高血压的总患病率较低,但呈上升趋势。确定了影响未确诊高血压的个体水平变量。因此,建议保持健康的生活方式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9803/11343413/aeaae66ce3c3/pone.0303940.g001.jpg

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