银屑病：家族易感性与环境因素
Psoriasis: familial predisposition and environmental factors.
作者信息
Kavli G, Førde O H, Arnesen E, Stenvold S E
出版信息
Br Med J (Clin Res Ed). 1985 Oct 12;291(6501):999-1000. doi: 10.1136/bmj.291.6501.999.
In a survey for coronary risk factors 14 667 adult men and women answered a questionnaire on lifestyle, diet, and health, including whether they had psoriasis. The overall prevalence of psoriasis was 4.79% in men and 4.85% in women. The data showed an increasing incidence of psoriasis. The association with family history, lifestyle, diet, and health was explored by multiple regression analysis. The occurrence of psoriasis in first degree relatives contributed to more than 90% of the explained variance for both sexes. Of the other variables, only the positive association with rheumatoid arthritis was significant in both sexes. It is concluded that the examined environmental factors have only minor effects on the prevalence of psoriasis.
在一项关于冠心病风险因素的调查中，14667名成年男性和女性回答了一份关于生活方式、饮食和健康状况的问卷，其中包括他们是否患有银屑病。银屑病的总体患病率在男性中为4.79%，在女性中为4.85%。数据显示银屑病的发病率呈上升趋势。通过多元回归分析探讨了银屑病与家族史、生活方式、饮食和健康状况之间的关联。一级亲属中银屑病的发生对男女双方超过90%的可解释变异有影响。在其他变量中，只有与类风湿性关节炎的正相关在男女双方中都具有显著性。研究得出结论，所研究的环境因素对银屑病患病率的影响较小。
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