Xue Yunfei, Zhao Wenzheng, Meng Qingxin, Yang Linfu, Zhi Dandan, Guo Yulong, Yue Dan, Tian Yakai, Dong Kun
Yunnan Provincial Engineering and Research Center for Sustainable Utilization of Honeybee Resources, Eastern Bee Research Institute, College of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China.
Insects. 2024 Aug 27;15(9):644. doi: 10.3390/insects15090644.
Glyphosate (GY) is the most widely used herbicide in agriculture worldwide. Lead is a common heavy metal in the natural environment. Honeybees, as pollinators, are exposed to these pollutants. So far, few reports have evaluated the toxic effects of GY mixed with heavy metals on honeybees (). This study found that the acute toxicity of lead (LC50 = 1083 mg/L) is much greater than that of GY (LC50 = 4764 mg/L) at 96 h. The acute toxicities of the mixed substances were as follows: LC50 = 621 mg/L of lead and LC50 = 946 mg/L of GY. The combination of lead and GY was more toxic than either of the individual substances alone. Compared to the individual toxicity, combined treatment significantly affected the bees' learning and cognitive abilities and changed the relative expression of genes related to immune defense and detoxification metabolism in . The combination of lead and GY seriously affected the behavior and physiology of the studied honeybees. This study provides basic data for further research on the combined effects of GY and heavy metals on bee health. It also serves as a reference for effective colony protection.
草甘膦（GY）是全球农业中使用最广泛的除草剂。铅是自然环境中常见的重金属。蜜蜂作为传粉者，会接触到这些污染物。到目前为止，很少有报告评估草甘膦与重金属混合对蜜蜂的毒性作用（）。本研究发现，在96小时时，铅的急性毒性（LC50 = 1083毫克/升）远大于草甘膦（LC50 = 4764毫克/升）。混合物质的急性毒性如下：铅的LC50 = 621毫克/升，草甘膦的LC50 = 946毫克/升。铅和草甘膦的组合比单独的任何一种物质毒性都更大。与单独的毒性相比，联合处理显著影响蜜蜂的学习和认知能力，并改变了与免疫防御和解毒代谢相关基因的相对表达。铅和草甘膦的组合严重影响了所研究蜜蜂的行为和生理。本研究为进一步研究草甘膦和重金属对蜜蜂健康的联合影响提供了基础数据。它也为有效的蜂群保护提供了参考。
