Ehrenfeld M, Nesher R, Merin S
Br J Ophthalmol. 1986 Apr;70(4):281-3. doi: 10.1136/bjo.70.4.281.
Delayed-onset chloroquine retinopathy was diagnosed in a patient seven years after cessation of treatment by a total dose of 730 g of chloroquine for rheumatoid arthritis. Visual functions continued to deteriorate after the diagnosis. Periodic examinations by ophthalmoscopy and by functional tests such as EOG and visual fields should be continued in patients at risk of delayed-onset chloroquine retinopathy after discontinuance of the drug.
一名类风湿关节炎患者在停用总量为730克氯喹治疗七年后被诊断出迟发性氯喹视网膜病变。诊断后视觉功能持续恶化。对于停用药物后有迟发性氯喹视网膜病变风险的患者,应继续通过检眼镜检查以及诸如眼电图和视野等功能测试进行定期检查。